Fracture healing-orthobiologics: from basic science to clinical application.
basic science
orthobiologics
research
Journal
OTA international : the open access journal of orthopaedic trauma
ISSN: 2574-2167
Titre abrégé: OTA Int
Pays: United States
ID NLM: 101770383
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
20
10
2022
accepted:
30
12
2022
medline:
12
5
2023
pubmed:
12
5
2023
entrez:
11
5
2023
Statut:
epublish
Résumé
Orthopaedics as a field and a profession is fundamentally concerned with the treatment of musculoskeletal disease, in all of its many forms. Our collective understanding of the cellular mechanisms underlying musculoskeletal pathology resulting from injury continues to evolve, opening novel opportunities to develop orthobiologic treatments to improve care. It is a long path to move from an understanding of cellular pathology to development of successful clinical treatment, and this article proposes to discuss some of the challenges to achieving translational therapies in orthopaedics. The article will focus on challenges that clinicians will likely face in seeking to bring promising treatments forward to clinical practice and strategies for improving success in translational efforts.
Identifiants
pubmed: 37168028
doi: 10.1097/OI9.0000000000000262
pii: OTAI-D-22-00072
pmc: PMC10166332
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e262Informations de copyright
Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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