Analyses of cytokine gene expression and fecal microbiota in a patient with Cronkhite-Canada syndrome successfully treated with prednisolone.
Cronkhite–Canada syndrome
cytokine
microbiota
polyposis
prednisolone
Journal
DEN open
ISSN: 2692-4609
Titre abrégé: DEN Open
Pays: Australia
ID NLM: 9918317682706676
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
25
01
2023
revised:
16
02
2023
accepted:
26
02
2023
medline:
12
5
2023
pubmed:
12
5
2023
entrez:
11
5
2023
Statut:
epublish
Résumé
Although prednisolone treatment is effective in Cronkhite-Canada syndrome (CCS), its mechanisms of action are poorly understood. We performed analyses of cytokine expression and fecal microbiota in a patient with the concurrent occurrence of CCS and rectal cancer, in whom regression of polyposis was achieved by prednisolone. Regression of CCS polyps was accompanied by downregulation of proinflammatory cytokine expression and alterations in microbiota composition; a decrease in
Identifiants
pubmed: 37168272
doi: 10.1002/deo2.222
pii: DEO2222
pmc: PMC10165462
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e222Informations de copyright
© 2023 The Authors. DEN Open published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.
Déclaration de conflit d'intérêts
None.
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