Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma.

cancer outcomes head and neck cancer oropharynx particle therapy

Journal

International journal of particle therapy
ISSN: 2331-5180
Titre abrégé: Int J Part Ther
Pays: United States
ID NLM: 101674108

Informations de publication

Date de publication:
2023
Historique:
received: 25 08 2022
accepted: 10 03 2023
medline: 12 5 2023
pubmed: 12 5 2023
entrez: 11 5 2023
Statut: epublish

Résumé

To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). A review of the pertinent literature. Proton beam therapy likely results in reduced acute and late toxicity as compared with intensity-modulated radiation therapy (IMRT). The extent of the reduced toxicity, which may be modest, depends on the endpoint and technical factors such as pencil beam versus passive scattered PBT and adaptive replanning. The disease control rates after PBT are likely similar to those after IMRT. Proton beam therapy is an attractive option to treat patients with OPSCC. Whether it becomes widely available depends on access.

Identifiants

pubmed: 37169005
doi: 10.14338/IJPT-22-00030.1
pmc: PMC10166016
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

243-252

Informations de copyright

©Copyright 2023 The Author(s).

Déclaration de conflit d'intérêts

Conflicts of Interest: William M. Mendenhall, MD, is the Advisory Editor of the International Journal of Particle Therapy. The authors have no additional relevant conflicts of interest to disclose.

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Auteurs

William M Mendenhall (WM)

Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.

Jonathan J Beitler (JJ)

Harold Alfonds Center for Cancer Care, Maine General Hospital, Augusta, ME, USA.

Nabil F Saba (NF)

Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.

Ashok R Shaha (AR)

Department of Head and Neck Surgery and Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Sandra Nuyts (S)

Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Laboratory of Experimental Radiotherapy, Department of Oncology, University of Leuven, Leuven, Belgium.

Primož Strojan (P)

Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.

Heleen Bollen (H)

Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.

Oded Cohen (O)

Department of Otolaryngology - Head and Neck Surgery and Oncology, Soroka Medical Center, Tel Aviv, Affiliated with Ben Gurion University of the Negev, Beer Sheva, Israel.

Robert Smee (R)

Department of Radiation Oncology, The Prince of Wales Cancer Centre, Sydney, NSW, Australia.

Sweet Ping Ng (SP)

Department of Radiation Oncology, Olivia Newton-John Cancer Centre, Austin Health, Melbourne, Australia.

Avraham Eisbruch (A)

Department of Radiation Oncology, University of Michigan Medicine, Ann Arbor, Michigan, USA.

Wai Tong Ng (WT)

Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Jessica M Kirwan (JM)

Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.

Alfio Ferlito (A)

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

Classifications MeSH