ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.
Journal
Nature neuroscience
ISSN: 1546-1726
Titre abrégé: Nat Neurosci
Pays: United States
ID NLM: 9809671
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
received:
09
08
2019
accepted:
11
04
2023
medline:
8
6
2023
pubmed:
12
5
2023
entrez:
11
5
2023
Statut:
ppublish
Résumé
Molecular diversity of microglia, the resident immune cells in the CNS, is reported. Whether microglial subsets characterized by the expression of specific proteins constitute subtypes with distinct functions has not been fully elucidated. Here we describe a microglial subtype expressing the enzyme arginase-1 (ARG1; that is, ARG1
Identifiants
pubmed: 37169859
doi: 10.1038/s41593-023-01326-3
pii: 10.1038/s41593-023-01326-3
pmc: PMC10244174
doi:
Substances chimiques
Arginase
EC 3.5.3.1
Arg1 protein, mouse
EC 3.5.3.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1008-1020Informations de copyright
© 2023. The Author(s).
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