Exploring the independent association of employment status to cancer survivors' health-related quality of life.
Age
Cancer survivors
Cancer type
Employment status
Marital status
Quality of life
Survival phase
Journal
Health and quality of life outcomes
ISSN: 1477-7525
Titre abrégé: Health Qual Life Outcomes
Pays: England
ID NLM: 101153626
Informations de publication
Date de publication:
11 May 2023
11 May 2023
Historique:
received:
20
05
2022
accepted:
29
04
2023
medline:
15
5
2023
pubmed:
12
5
2023
entrez:
11
5
2023
Statut:
epublish
Résumé
Having a job has been associated with better Health-Related Quality of Life (HRQOL) in cancer survivors. However, the sociodemographic and disease-related profiles characterizing the survivors being employed and those having better HRQOL largely overlap. The present study aims to discern the degree to which employment status is independently associated with cancer survivors' HRQOL or if it mainly reflects the impact of other sociodemographic and cancer-related variables. Cross-sectional study on a heterogeneous sample of 772 working-age survivors of adult-onset cancer. An instrument specifically designed to assess HRQOL in cancer survivors and Multivariate Variance Analysis (MANOVA) were used. Survival phase, cancer type, and employment status showed the main effects on cancer survivors' HRQOL. In particular, being employed (vs unemployed) had the greatest positive association with HRQOL, affecting ten of the twelve HRQOL domains considered. Also, interaction effects highlighted the role of age (younger) and marital status (single) as risk factors for a greater negative impact of variables affecting the survivor's HRQOL. The application of a multivariate methodology sheds new light on two relevant issues for the cancer survivor's HRQOL: (i) the existence of differences between diagnostic groups that are not attributed to other variables such as sex, and (ii) the important and independent role that employment status plays. Comprehensive cancer survivorship care should focus more on high-risk groups and include having a job as an essential aspect to consider and prompt. The fact that the employment status is susceptible to change represents a valuable opportunity to care for the wellbeing of this population.
Sections du résumé
BACKGROUND
BACKGROUND
Having a job has been associated with better Health-Related Quality of Life (HRQOL) in cancer survivors. However, the sociodemographic and disease-related profiles characterizing the survivors being employed and those having better HRQOL largely overlap. The present study aims to discern the degree to which employment status is independently associated with cancer survivors' HRQOL or if it mainly reflects the impact of other sociodemographic and cancer-related variables.
METHODS
METHODS
Cross-sectional study on a heterogeneous sample of 772 working-age survivors of adult-onset cancer. An instrument specifically designed to assess HRQOL in cancer survivors and Multivariate Variance Analysis (MANOVA) were used.
RESULTS
RESULTS
Survival phase, cancer type, and employment status showed the main effects on cancer survivors' HRQOL. In particular, being employed (vs unemployed) had the greatest positive association with HRQOL, affecting ten of the twelve HRQOL domains considered. Also, interaction effects highlighted the role of age (younger) and marital status (single) as risk factors for a greater negative impact of variables affecting the survivor's HRQOL.
CONCLUSIONS
CONCLUSIONS
The application of a multivariate methodology sheds new light on two relevant issues for the cancer survivor's HRQOL: (i) the existence of differences between diagnostic groups that are not attributed to other variables such as sex, and (ii) the important and independent role that employment status plays. Comprehensive cancer survivorship care should focus more on high-risk groups and include having a job as an essential aspect to consider and prompt. The fact that the employment status is susceptible to change represents a valuable opportunity to care for the wellbeing of this population.
Identifiants
pubmed: 37170308
doi: 10.1186/s12955-023-02124-y
pii: 10.1186/s12955-023-02124-y
pmc: PMC10176702
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
44Informations de copyright
© 2023. The Author(s).
Références
Radiother Oncol. 2018 Feb;126(2):283-290
pubmed: 29273262
Gastric Cancer. 2018 May;21(3):524-532
pubmed: 29067597
J Occup Rehabil. 2012 Mar;22(1):71-7
pubmed: 21870065
J Cancer Surviv. 2022 Apr;16(2):397-407
pubmed: 33907994
Int J Environ Res Public Health. 2019 Apr 14;16(8):
pubmed: 31014004
Support Care Cancer. 2021 Sep;29(9):5151-5160
pubmed: 33611646
J Clin Oncol. 2020 Mar 1;38(7):734-743
pubmed: 31834818
Support Care Cancer. 2018 Feb;26(2):651-656
pubmed: 28918552
Cancer Med. 2021 Jun;10(12):3938-3951
pubmed: 33991067
Lancet Oncol. 2017 Jan;18(1):e11-e18
pubmed: 28049573
Cancer. 2013 Jun 1;119 Suppl 11:2151-9
pubmed: 23695927
J Natl Cancer Inst. 2014 Nov 27;107(1):335
pubmed: 25432407
Support Care Cancer. 2018 Sep;26(9):2983-2994
pubmed: 29845421
PLoS One. 2020 Jan 29;15(1):e0227792
pubmed: 31995590
Qual Life Res. 2022 Jun;31(6):1871-1881
pubmed: 34837128
J Natl Compr Canc Netw. 2021 Jun 30;19(6):676-685
pubmed: 34214969
Support Care Cancer. 2022 Feb;30(2):1483-1491
pubmed: 34529142
J Cancer Surviv. 2010 Dec;4(4):415-37
pubmed: 20945110
CA Cancer J Clin. 2018 Jan;68(1):7-30
pubmed: 29313949
Support Care Cancer. 2017 May;25(5):1475-1484
pubmed: 28019005
Qual Life Res. 2016 Feb;25(2):409-421
pubmed: 26289021
Br J Cancer. 2021 Aug;125(5):759-765
pubmed: 34127810
JAMA. 2009 Feb 18;301(7):753-62
pubmed: 19224752
Health Qual Life Outcomes. 2020 Nov 2;18(1):353
pubmed: 33138835
J Natl Cancer Inst. 2018 Dec 1;110(12):1292-1299
pubmed: 30346557
Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2108-17
pubmed: 23112268
Cancer. 2017 Feb 1;123(3):476-484
pubmed: 27716900
Asian Pac J Cancer Prev. 2014;15(13):5287-91
pubmed: 25040990
Cancer Epidemiol. 2019 Jun;60:201-207
pubmed: 31071525
EJC Suppl. 2014 Jun;12(1):54-64
pubmed: 26217166
CA Cancer J Clin. 2019 Sep;69(5):363-385
pubmed: 31184787
Acta Oncol. 2017 Feb;56(2):174-182
pubmed: 28093023
Support Care Cancer. 2020 Sep;28(9):4435-4443
pubmed: 31919668
Neoplasma. 2020 Mar;67(2):389-393
pubmed: 31986888
Psychooncology. 2013 Jun;22(6):1208-19
pubmed: 22888070
Crit Rev Oncol Hematol. 2011 Feb;77(2):109-30
pubmed: 20117019
Mol Oncol. 2019 Mar;13(3):624-635
pubmed: 30552794
Cancer. 2013 Feb 1;119(3):672-80
pubmed: 22951588
J Psychol. 2004 Sep;138(5):404-20
pubmed: 15529735
J Natl Cancer Inst. 2018 Oct 1;110(10):1041-1047
pubmed: 30252079
Ann Hematol. 2015 Apr;94(4):651-61
pubmed: 25471174
Ann Surg. 2014 Mar;259(3):569-75
pubmed: 23657081
Qual Life Res. 2005 May;14(4):1007-23
pubmed: 16041897
Psychooncology. 2002 Mar-Apr;11(2):124-31
pubmed: 11921328
Int J Psychiatry Med. 2010;40(2):163-81
pubmed: 20848873
J Cancer Surviv. 2018 Oct;12(5):712-720
pubmed: 30097854
Eur J Cancer Care (Engl). 2022 Nov;31(6):e13692
pubmed: 36069249
Pain. 2000 Mar;85(1-2):19-30
pubmed: 10692599
Health Qual Life Outcomes. 2015 Nov 16;13:182
pubmed: 26573805
Asian Pac J Cancer Prev. ;18(10):2809-2816
pubmed: 29072421
Adv Exp Med Biol. 2015;862:231-42
pubmed: 26059939
Cancers (Basel). 2020 Mar 16;12(3):
pubmed: 32187972
Dtsch Arztebl Int. 2008 Oct;105(41):706-14
pubmed: 19623293
Cochrane Database Syst Rev. 2015 Sep 25;(9):CD007569
pubmed: 26405010
Qual Life Res. 2015 Apr;24(4):959-67
pubmed: 25342116
J Cancer Surviv. 2017 Dec;11(6):765-781
pubmed: 28478587
J Cancer Surviv. 2020 Aug;14(4):504-517
pubmed: 32162194
Int J Environ Res Public Health. 2020 Dec 14;17(24):
pubmed: 33327622
Int Arch Occup Environ Health. 2021 Feb;94(2):147-189
pubmed: 32929528
Sci Rep. 2022 Nov 4;12(1):18673
pubmed: 36333362
Support Care Cancer. 2020 Jan;28(1):185-192
pubmed: 31001691