Thromboelastographic evaluation after cardiac surgery optimizes transfusion requirements in the intensive care unit: a single-center retrospective cohort study using an inverse probability weighting method.

Cardiac surgery Intensive care unit Patient blood management Thromboelastography Transfusion

Journal

General thoracic and cardiovascular surgery
ISSN: 1863-6713
Titre abrégé: Gen Thorac Cardiovasc Surg
Pays: Japan
ID NLM: 101303952

Informations de publication

Date de publication:
12 May 2023
Historique:
received: 13 02 2023
accepted: 07 05 2023
medline: 13 5 2023
pubmed: 13 5 2023
entrez: 12 5 2023
Statut: aheadofprint

Résumé

There are no reports from Japan showing the effects of using the thromboelastography algorithm on transfusion requirements after Intensive Care Unit (ICU) admission, and post-implementation knowledge regarding the thromboelastography algorithm under the Japanese healthcare system is insufficient. Therefore, this study aimed to clarify the effect of the TEG6s thromboelastography algorithm on transfusion requirements for patients in the ICU after cardiac surgery. We retrospectively compared the requirements for blood transfusion up to 24 h after ICU admission using the thromboelastography algorithm (January 2021 to April 2022) (thromboelastography group; n = 201) and specialist consultation with surgeons and anesthesiologists (January 2018 to December 2020) (non-thromboelastography group; n = 494). There were no significant between-group differences in terms of age, height, weight, body mass index, operative procedure, duration of surgery or cardiopulmonary bypass, body temperature, or urine volume during surgical intervention. Moreover, there was no significant between-group difference in the amount of drainage at 24 h after ICU admission. However, crystalloid and urine volumes were significantly higher in the thromboelastography group than in the non-thromboelastography group. Additionally, fresh-frozen plasma (FFP) transfusion volumes were significantly lower in the thromboelastography group. However, there were no significant between-group differences in red blood cell count or platelet transfusion volume. After variable adjustment, the amount of FFP used from the operating room to 24 h after ICU admission was significantly reduced in the thromboelastography group. The thromboelastography algorithm optimized transfusion requirements at 24 h after admission to the ICU following cardiac surgery.

Identifiants

pubmed: 37173610
doi: 10.1007/s11748-023-01941-8
pii: 10.1007/s11748-023-01941-8
pmc: PMC10180616
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s), under exclusive licence to The Japanese Association for Thoracic Surgery.

Références

Can J Anaesth. 2004 Apr;51(4):293-310
pubmed: 15064258
Front Med (Lausanne). 2015 Sep 14;2:62
pubmed: 26442265
Anesthesiology. 2012 Sep;117(3):531-47
pubmed: 22914710
Vox Sang. 2015 Oct;109(3):267-79
pubmed: 25930098
Anesthesiology. 2011 Dec;115(6):1179-91
pubmed: 21970887
J Thorac Cardiovasc Surg. 2010 Nov;140(5):1117-24.e2
pubmed: 20951260
J Clin Anesth. 2019 Dec;58:59-60
pubmed: 31078915
J Thromb Haemost. 2003 Jul;1(7):1504-14
pubmed: 12871286
Transfusion. 2019 Jun;59(6):2023-2029
pubmed: 30882929
Br J Anaesth. 2001 Apr;86(4):575-8
pubmed: 11573637
Anesthesiology. 2015 Mar;122(3):560-70
pubmed: 25485470
Curr Opin Anaesthesiol. 2014 Apr;27(2):212-8
pubmed: 24514038
Clin Lab Med. 2014 Sep;34(3):453-77
pubmed: 25168937
Anesthesiology. 2015 Feb;122(2):241-75
pubmed: 25545654
Eur J Anaesthesiol. 2013 Jun;30(6):270-382
pubmed: 23656742
Crit Care Clin. 2004 Jan;20(1):13-24
pubmed: 14979327
Anesth Analg. 1999 Feb;88(2):312-9
pubmed: 9972747
Br J Anaesth. 2015 Feb;114(2):217-24
pubmed: 25204698

Auteurs

Takahiro Tamura (T)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. takahiro@med.nagoya-u.ac.jp.

Shogo Suzuki (S)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Tasuku Fujii (T)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Takahiro Hirai (T)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Takahiro Imaizumi (T)

Department of Advanced Medicine, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Department of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Yoko Kubo (Y)

Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Yasuyuki Shibata (Y)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Yuji Narita (Y)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Masato Mutsuga (M)

Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Kimitoshi Nishiwaki (K)

Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.

Classifications MeSH