Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models.
GEMMs
KRAS
RAC1
VAV1
p53
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
27 04 2023
27 04 2023
Historique:
received:
29
03
2023
revised:
23
04
2023
accepted:
24
04
2023
medline:
15
5
2023
pubmed:
13
5
2023
entrez:
13
5
2023
Statut:
epublish
Résumé
VAV1 is a hematopoietic signal transducer that possesses a GDP/GTP nucleotide exchange factor (GEF) that is tightly regulated by tyrosine phosphorylation, along with adapter protein domains, such as SH2 and SH3. Research on
Identifiants
pubmed: 37174676
pii: cells12091276
doi: 10.3390/cells12091276
pmc: PMC10177506
pii:
doi:
Substances chimiques
Proto-Oncogene Proteins c-vav
0
VAV1 protein, human
0
Vav1 protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Références
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