Acetogenins-Rich Fractions of
Annona coriacea
Annonaceae
GBM
acetogenins
gliomas
matrix metalloproteinase
mechanism of death
natural product
necroptosis
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
29 Apr 2023
29 Apr 2023
Historique:
received:
02
01
2023
revised:
18
01
2023
accepted:
21
01
2023
medline:
15
5
2023
pubmed:
13
5
2023
entrez:
13
5
2023
Statut:
epublish
Résumé
Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection, radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the treatment limited. Thus, the search for more effective and specific treatments is essential, making plants a promising source for elucidating new anti-glioblastoma compounds. Accordingly, this study investigated the effects of four fractions of hexane and ethyl acetate extract of
Identifiants
pubmed: 37175219
pii: molecules28093809
doi: 10.3390/molecules28093809
pmc: PMC10179884
pii:
doi:
Substances chimiques
Matrix Metalloproteinase 2
EC 3.4.24.24
Acetogenins
0
Temozolomide
YF1K15M17Y
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de Minas Gerais
ID : PPM-00229-16 and APQ-00068-18
Organisme : Coordenação de Aperfeicoamento de Pessoal de Nível Superior
ID : Finance Code 001
Organisme : Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education
ID : NRF-2020R1I1A2066868
Organisme : National Research Foundation of Korea
ID : No. 2020R1A5A2019413
Organisme : Financiadora de Estudos e Projetos
ID : MCTI/FINEP/MS/SCTIE/DECIT-01/2013, FPXII-BIOPLAT
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