Plasma Antithrombin III Levels Can Be a Prognostic Factor in Liver Cirrhosis Patients with Portal Vein Thrombosis.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
23 Apr 2023
Historique:
received: 28 01 2023
revised: 12 04 2023
accepted: 20 04 2023
medline: 15 5 2023
pubmed: 13 5 2023
entrez: 13 5 2023
Statut: epublish

Résumé

Liver function influences the plasma antithrombin (AT)-III levels. AT-III is beneficial for patients with portal vein thrombosis (PVT) and low plasma AT-III levels. However, whether these levels affect prognosis in patients with cirrhosis-associated PVT remains unknown. This retrospective study involved 75 patients with cirrhosis and PVT treated with danaparoid sodium with or without AT-III. The plasma AT-III level was significantly lower in patients with liver failure-related death than in those with hepatocellular carcinoma (HCC)-related death (

Identifiants

pubmed: 37175438
pii: ijms24097732
doi: 10.3390/ijms24097732
pmc: PMC10178007
pii:
doi:

Substances chimiques

Antithrombin III 9000-94-6
Anticoagulants 0
Bilirubin RFM9X3LJ49
Albumins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Japan Society for the Promotion of Science
ID : 20K08280-00

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Auteurs

Tsuyoshi Suda (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Hajime Takatori (H)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Takehiro Hayashi (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Kiichiro Kaji (K)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Kouki Nio (K)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Takeshi Terashima (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Tetsuro Shimakami (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Kuniaki Arai (K)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Tatsuya Yamashita (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Eishiro Mizukoshi (E)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Masao Honda (M)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Kenichiro Okumura (K)

Department of Radiology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Kazuto Kozaka (K)

Department of Radiology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

Taro Yamashita (T)

Department of Gastroenterology, Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan.

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Classifications MeSH