Use of Steroids in Spine Surgery.
Journal
The Journal of the American Academy of Orthopaedic Surgeons
ISSN: 1940-5480
Titre abrégé: J Am Acad Orthop Surg
Pays: United States
ID NLM: 9417468
Informations de publication
Date de publication:
01 Jul 2023
01 Jul 2023
Historique:
received:
07
12
2022
accepted:
01
03
2023
medline:
19
6
2023
pubmed:
15
5
2023
entrez:
15
5
2023
Statut:
ppublish
Résumé
Steroids are commonly used in spine pathologies. A broad range of providers from different specialties such as primary care, emergency medicine, and spine surgeons use steroids. The indications and controversies of steroid use are discussed in this article. A literature review was conducted on the use of steroids in spine pathologies. Steroids have been successfully used in anterior cervical discectomy and fusion (ACDF) to prevent dysphagia, in spinal cord injuries to improve neurological function, in acute back and neck pain for pain control, and in spinal metastasis. Steroid injections have been used for axial as well as radicular pain. Techniques and complications are further discussed. Local and systemic steroids have been successful in preventing dysphagia after anterior cervical diskectomy and fusion. Steroids failed to improve the neurologic outcomes after spinal cord injuries, and they were associated with multiple complications. Systemic steroids have not been proven to provide better clinical outcomes for acute low back pain. Steroid injections are more effective in radicular pain rather than axial pain. There are not enough high-quality studies on the use of steroids for metastatic spinal cord compression.
Identifiants
pubmed: 37184471
doi: 10.5435/JAAOS-D-22-00971
pii: 00124635-202307010-00001
doi:
Substances chimiques
Steroids
0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
651-659Informations de copyright
Copyright © 2023 by the American Academy of Orthopaedic Surgeons.
Références
Ramamoorthy S, Cidlowski JA. Corticosteroids: Mechanisms of action in health and disease. Rheum Dis Clin North Am 2016;42:15-31.
Williams DM: Clinical pharmacology of corticosteroids. Respir Care 2018;63:655-670.
Cruz-Topete D, Cidlowski JA: One hormone, two actions: Anti- and pro-inflammatory effects of glucocorticoids. Neuroimmunomodulation 2015;22:20-32.
Makkar JK, Singh PM, Jain D, Goudra B: Particulate vs non-particulate steroids for transforaminal epidural steroid injections: Systematic review and meta-analysis of the current literature. Pain Physician 2016;6;19:327-340.
Okano I, Salzmann SN, Ortiz Miller C, et al.: Risk factors for postoperative dysphagia and dysphonia following anterior cervical spine surgery: A comprehensive study utilizing the hospital for special surgery dysphagia and dysphonia inventory (HSS-DDI). Spine J 2021;21:1080-1088.
Zadegan SA, Jazayeri SB, Abedi A, Bonaki HN, Vaccaro AR, Rahimi-Movaghar V: Corticosteroid administration to prevent complications of anterior cervical spine fusion: A systematic review. Glob Spine J 2018;8:286-302.
Cui S, Daffner SD, France JC, Emery SE: The effects of perioperative corticosteroids on dysphagia following surgical procedures involving the anterior cervical spine: A prospective, randomized, controlled, double-blinded clinical trial. J Bone Joint Surg Am 2019;101:2007-2014.
Kim HJ, Alluri R, Stein D, et al. Effect of topical steroid on swallowing following ACDF: Results of a prospective double-blind randomized control trial. Spine (Phila Pa 1976) 2021;46:413-420.
Jenkins TJ, Nair R, Bhatt S, et al.: The effect of local versus intravenous corticosteroids on the likelihood of dysphagia and dysphonia following anterior cervical discectomy and fusion: A single-blinded, prospective, randomized controlled trial. J Bone Joint Surg Am 2018;100:1461-1472.
Yu H, Dong H, Ruan B, Xu X, Wang Y: Intraoperative use of topical retropharyngeal steroids for dysphagia after anterior cervical fusion: A systematic review and meta-analysis. Dis Markers 2021;2021:1-9.
Song J, Yi P, Wang Y, et al.: The retropharyngeal steroid use during operation on the fusion rate and dysphagia after ACDF? A systematic review and meta-analysis. Eur Spine J 2022;31:288-300.
Jeyamohan SB, Kenning TJ, Petronis KA, Feustel PJ, Drazin D, DiRisio DJ: Effect of steroid use in anterior cervical discectomy and fusion: A randomized controlled trial. J Neurosurg Spine 2015;23:137-143.
Sultan I, Lamba N, Liew A, et al.: The safety and efficacy of steroid treatment for acute spinal cord injury: A systematic review and meta-analysis. Heliyon 2020;6:e03414.
Fehlings MG, Wilson JR, Tetreault LA, et al. A clinical practice guideline for the management of patients with acute spinal cord injury: Recommendations on the use of methylprednisolone sodium succinate. Glob Spine J. 2017;7:203S-211S.
Kurisunkal V, Gulia A, Gupta S: Principles of management of spine metastasis. Indian J Orthopaedics 2020;54:181-193.
Skeoch GD, Tobin MK, Khan S, Linninger AA, Mehta AI: Corticosteroid treatment for metastatic spinal cord compression: A review. Glob Spine J 2017;7:272-279.
Kumar A, Weber MH, Gokaslan Z, et al.: Metastatic spinal cord compression and steroid treatment: A systematic review. Clin Spine Surg 2017;30:156-163.
Maranzano E, Latini P, Beneventi S, et al.: Radiotherapy without steroids in selected metastatic spinal cord compression patients. A phase II trial. Am J Clin Oncol 1996;19:179-183.
Chou R, Pinto RZ, Fu R, Lowe RA, Henschke N, Dana T: Systemic corticosteroids for radicular and non‐radicular low back pain. Cochrane Database Syst Rev 2016.
Finckh A, Zufferey P, Schurch MA, Balague F, Waldburger M, So AKL: Short-term efficacy of intravenous pulse glucocorticoids in acute discogenic sciatica. A randomized controlled trial. Spine (Phila Pa 1976) 2006;31:377-381.
Friedman BW, Holden L, Esses D, et al.: Parenteral corticosteroids for Emergency Department patients with non-radicular low back pain. J Emerg Med 2006;31:365-370.
North American Spine Society: Epidural Steroid Injection and Selective Spinal Nerve Blocks. North American Spine Society (NASS), 2020.
Benyamin RM, Manchikanti L, Parr AT: The effectiveness of lumbar interlaminar epidural injections in managing chronic low back and lower extremity pain. Pain Physician 2012;4;15:E363-E404.
Staal JB, de Bie RA, de Vet HCW, Hildebrandt J, Nelemans P: Injection therapy for subacute and chronic low back pain: An updated Cochrane review. Spine (Phila Pa 1976) 2009;34:49-59.
Brogly N, Guasch E, Alsina E, et al.: Epidural space identification with loss of resistance technique for epidural analgesia during labor: A randomized controlled study using air or saline-new arguments for an old controversy. Anesth Analg 2018;126:532-536.
House LM, Barrette K, Mattie R, McCormick ZL: Cervical epidural steroid injection: Techniques and evidence. Phys Med Rehabil Clin N Am 2018;29:1-17.
Ghahreman A, Ferch R, Bogduk N: The efficacy of transforaminal injection of steroids for the treatment of lumbar radicular pain. Pain Med 2010;11:1149-1168.
Lee JH, Moon J, Lee SH: Comparison of effectiveness according to different approaches of epidural steroid injection in lumbosacral herniated disk and spinal stenosis. J Back Musculoskelet Rehabil 2009;22:83-89.
White AH, Derby R, Wynne G: Epidural injections for the diagnosis and treatment of low-back pain. Spine (Phila Pa 1976) 1980;5:78-86.
Botwin KP, Natalicchio J, Hanna A: Fluoroscopic guided lumbar interlaminar epidural injections: A prospective evaluation of epidurography contrast patterns and anatomical review of the epidural space. Pain Physician 2004;1;7:77-80.
Goodman BS, House LM, Vallabhaneni S, Mallempati S, Willey MR, Smith MT: Anticoagulant and antiplatelet management for spinal procedures: A prospective, descriptive study and interpretation of guidelines. Pain Med 2017;18:1218-1224.
Ahmed SV, Jayawarna C, Jude E: Post lumbar puncture headache: Diagnosis and management. Postgrad Med J 2006;82:713-716.