Biologicals in IgE-mediated food allergy.


Journal

Current opinion in allergy and clinical immunology
ISSN: 1473-6322
Titre abrégé: Curr Opin Allergy Clin Immunol
Pays: United States
ID NLM: 100936359

Informations de publication

Date de publication:
01 06 2023
Historique:
medline: 17 5 2023
pubmed: 15 5 2023
entrez: 15 5 2023
Statut: ppublish

Résumé

A better understanding of the most recent scientific literature in the use of biological therapy in the treatment of patients with IgE-mediated food allergy. A systematic review and meta-analysis demonstrated safety and effectiveness of omalizumab in the treatment of food allergy. The findings support the potential use of omalizumab as a monotherapy or as an adjunct to oral immunotherapy in IgE-mediated cow's milk allergy. The potential use of other biologics in the management of food allergy is subject of speculation. Different biological therapies are under evaluation for food allergic patients. The advance in literature will guide for a personalized treatment in the near future. However, additional research is needed to better understand the best candidate for each treatment, the optimal dose and timing.

Identifiants

pubmed: 37185824
doi: 10.1097/ACI.0000000000000900
pii: 00130832-202306000-00003
doi:

Substances chimiques

Omalizumab 2P471X1Z11
Biological Products 0
Immunoglobulin E 37341-29-0

Types de publication

Systematic Review Meta-Analysis Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

205-209

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Antonio Mutarelli (A)

Federal University of Minas Gerais, Belo Horizonte, MG.

Bruna Giavina-Bianchi (B)

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Stefania Arasi (S)

Allergy Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Arianna Cafarotti (A)

Federal University of Minas Gerais, Belo Horizonte, MG.
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Allergy Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Alessandro Fiocchi (A)

Allergy Diseases Research Area, Pediatric Allergology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

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