High risk lung nodule: A multidisciplinary approach to diagnosis and management.

Cryoablation Electromagnetic navigation Endobronchial ultrasound Lung cancer Lung nodule Radiofrequency ablation Robot assisted bronchoscopy SBRT VATS Lung resection

Journal

Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438

Informations de publication

Date de publication:
08 2023
Historique:
received: 09 11 2022
revised: 28 04 2023
accepted: 04 05 2023
medline: 29 5 2023
pubmed: 16 5 2023
entrez: 15 5 2023
Statut: ppublish

Résumé

Pulmonary nodules are often discovered incidentally during CT scans performed for other reasons. While the vast majority of nodules are benign, a small percentage may represent early-stage lung cancer with the potential for curative treatments. With the growing use of CT for both clinical purposes and lung cancer screening, the number of pulmonary nodules detected is expected to increase substantially. Despite well-established guidelines, many nodules do not receive proper evaluation due to a variety of factors, including inadequate coordination of care and financial and social barriers. To address this quality gap, novel approaches such as multidisciplinary nodule clinics and multidisciplinary boards may be necessary. As pulmonary nodules may indicate early-stage lung cancer, it is crucial to adopt a risk-stratified approach to identify potential lung cancers at an early stage, while minimizing the risk of harm and expense associated with over investigation of low-risk nodules. This article, authored by multiple specialists involved in nodule management, delves into the diagnostic approach to lung nodules. It covers the process of determining whether a patient requires tissue sampling or continued surveillance. Additionally, the article provides an in-depth examination of the various biopsy and therapeutic options available for malignant lung nodules. The article also emphasizes the significance of early detection in reducing lung cancer mortality, especially among high-risk populations. Furthermore, it addresses the creation of a comprehensive lung nodule program, which involves smoking cessation, lung cancer screening, and systematic evaluation and follow-up of both incidental and screen-detected nodules.

Identifiants

pubmed: 37187432
pii: S0954-6111(23)00165-8
doi: 10.1016/j.rmed.2023.107277
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

107277

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Babith J Mankidy (BJ)

Division of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, 1Baylor Plaza, Houston, TX, 77030, USA. Electronic address: Babith.Mankidy@bcm.edu.

GhasemiRad Mohammad (G)

Department of Radiology, Division of Vascular and Interventional Radiology, Baylor College of Medicine, USA. Electronic address: Mohammad.GhasemiRad@bcm.edu.

Kelly Trinh (K)

Texas Tech University Health Sciences Center, School of Medicine, USA. Electronic address: Kelly.Trinh@ttuhsc.edu.

Anoop P Ayyappan (AP)

Department of Radiology, Division of Thoracic Radiology, Baylor College of Medicine, USA. Electronic address: Anoop.Ayyappan@bcm.edu.

Quillan Huang (Q)

Department of Oncology, Baylor College of Medicine, USA. Electronic address: Quillanh@bcm.edu.

Steven Bujarski (S)

Division of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, 1Baylor Plaza, Houston, TX, 77030, USA. Electronic address: Steven.Bujarski@bcm.edu.

Mohammad S Jafferji (MS)

Department of Cardiothoracic Surgery, Baylor College of Medicine, USA. Electronic address: Mohammad.jafferji@bcm.edu.

Ravi Ghanta (R)

Department of Cardiothoracic Surgery, Baylor College of Medicine, USA. Electronic address: Ravi.Ghanta@bcm.edu.

Alexander N Hanania (AN)

Department of Radiation Oncology, Baylor College of Medicine, USA. Electronic address: Alex.Hanania@bcm.edu.

Donald R Lazarus (DR)

Division of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, 1Baylor Plaza, Houston, TX, 77030, USA. Electronic address: Donald.Lazarus@bcm.edu.

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Classifications MeSH