The Potassium Channel Blocker β-Bungarotoxin from the Krait

antiprotozoal activity ciliate krait potassium channel venom β-bungarotoxin

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
07 Apr 2023
Historique:
received: 28 01 2023
revised: 17 03 2023
accepted: 04 04 2023
medline: 16 5 2023
pubmed: 16 5 2023
entrez: 16 5 2023
Statut: epublish

Résumé

Protozoal infections are a world-wide problem. The toxicity and somewhat low effectiveness of the existing drugs require the search for new ways of protozoa suppression. Snake venom contains structurally diverse components manifesting antiprotozoal activity; for example, those in cobra venom are cytotoxins. In this work, we aimed to characterize a novel antiprotozoal component(s) in the

Identifiants

pubmed: 37189733
pii: biomedicines11041115
doi: 10.3390/biomedicines11041115
pmc: PMC10136136
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Russian Foundation for Basic Research
ID : 21-54-54005
Organisme : Vietnamese Academy of Sciences and Technology
ID : QTRU01.15/21-22

Références

Cell. 2007 Nov 2;131(3):505-15
pubmed: 17981118
PLoS Pathog. 2019 Jun 26;15(6):e1007828
pubmed: 31242261
Toxicon. 2022 Oct 15;217:96-106
pubmed: 35977615
Curr Drug Targets. 2022;23(2):126-144
pubmed: 35139779
Infect Disord Drug Targets. 2020;20(6):913-919
pubmed: 31903885
Bioorg Med Chem. 2017 Dec 15;25(24):6332-6344
pubmed: 29042223
Mol Pharmacol. 1990 Aug;38(2):164-9
pubmed: 2385229
Acta Trop. 2013 Oct;128(1):27-35
pubmed: 23770204
Anal Chem. 2002 Oct 1;74(19):4980-8
pubmed: 12380820
Toxins (Basel). 2016 Apr 13;8(4):110
pubmed: 27089366
Front Pharmacol. 2019 Nov 29;10:1415
pubmed: 31849667
Exp Parasitol. 2008 Dec;120(4):391-6
pubmed: 18823981
Drug Dev Res. 2019 Feb;80(1):68-85
pubmed: 30255943
PLoS Negl Trop Dis. 2016 Dec 27;10(12):e0005247
pubmed: 28027299
Biomed Res Int. 2014;2014:195356
pubmed: 24724078
PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3252
pubmed: 25330220
J Biochem. 1978 Nov;84(5):1301-8
pubmed: 730754
Br J Pharmacol. 2022 Dec;179(24):5237-5258
pubmed: 36165125
Pathogens. 2021 Dec 16;10(12):
pubmed: 34959587
Physiology (Bethesda). 2008 Aug;23:212-20
pubmed: 18697995
Peptides. 2016 Apr;78:11-6
pubmed: 26806200
Acta Parasitol. 2021 Jun;66(2):475-486
pubmed: 33159262
Bull Exp Biol Med. 2014 Jun;157(2):285-7
pubmed: 24952500
Br J Pharmacol. 1988 Jul;94(3):839-47
pubmed: 3263160
Brief Bioinform. 2018 Sep 28;19(5):954-970
pubmed: 28369237
Toxicon. 2016 Oct;121:70-76
pubmed: 27576061
PLoS Pathog. 2022 Dec 29;18(12):e1011004
pubmed: 36580479
Exp Parasitol. 2013 Sep;135(1):126-33
pubmed: 23830987
PLoS One. 2016 Aug 23;11(8):e0159423
pubmed: 27552222
Toxins (Basel). 2012 Dec 14;4(12):1500-16
pubmed: 23242318
Rev Soc Bras Med Trop. 2016 Nov-Dec;49(6):752-757
pubmed: 28001223
PeerJ. 2019 Feb 27;7:e6430
pubmed: 30834181
Crit Rev Immunol. 1990;10(3):177-201
pubmed: 2085407
Int J Biol Macromol. 2020 Dec 1;164:616-625
pubmed: 32698062
Toxins (Basel). 2020 May 15;12(5):
pubmed: 32429047
Acta Trop. 2012 Nov;124(2):126-32
pubmed: 22884508
J Biochem Mol Toxicol. 2018 Feb;32(2):
pubmed: 29278277
Int J Mol Sci. 2022 Mar 26;23(7):
pubmed: 35408989
Nat Rev Microbiol. 2008 Nov;6(11):838-50
pubmed: 18923411
Int Immunopharmacol. 2018 Feb;55:128-132
pubmed: 29253818
J Pharmacol Exp Ther. 1997 Jul;282(1):262-70
pubmed: 9223563
J Parasit Dis. 2016 Sep;40(3):756-9
pubmed: 27605779
Anal Biochem. 1989 Feb 15;177(1):103-9
pubmed: 2742139
Sci Rep. 2022 Apr 16;12(1):6394
pubmed: 35430620
Chemosphere. 1999 Mar;38(7):1631-69
pubmed: 10070737
J Biochem. 1982 May;91(5):1519-30
pubmed: 7096304
Cell Struct Funct. 1988 Feb;13(1):51-60
pubmed: 2453296
Int J Biol Macromol. 2021 Jan 15;167:267-278
pubmed: 33242552
Semin Cell Dev Biol. 2015 Oct;46:113-27
pubmed: 26523344
Int J Biol Macromol. 2018 Dec;120(Pt A):431-439
pubmed: 30118767
Phytochemistry. 2009 Apr;70(6):703-12
pubmed: 19409579
Pathogens. 2020 Jan 25;9(2):
pubmed: 31991768
J Nat Prod. 2021 Jun 25;84(6):1787-1798
pubmed: 34077221
Dokl Biochem Biophys. 2022 Apr;503(1):98-103
pubmed: 35538287
Parasitology. 2018 Jul;145(8):1059-1064
pubmed: 29208061
Biochem J. 1994 Oct 1;303 ( Pt 1):171-6
pubmed: 7945237
J Chromatogr A. 1995 Mar 10;694(2):492-7
pubmed: 7704193
Toxicon. 2015 Dec 1;107(Pt B):197-209
pubmed: 26341420
Trends Parasitol. 2022 Jan;38(1):80-94
pubmed: 34364805
Mol Biol Evol. 2011 Mar;28(3):1319-31
pubmed: 21127172
Toxicon. 2012 Dec 1;60(7):1263-76
pubmed: 22963728
Toxicon. 2007 Jun 1;49(7):995-1001
pubmed: 17341427
Int J Biol Macromol. 2015 Sep;80:489-97
pubmed: 26162245
Rapid Commun Mass Spectrom. 2003;17(20):2337-42
pubmed: 14558135
Biochimie. 2019 Jul;162:97-106
pubmed: 30978375
Rev Physiol Biochem Pharmacol. 1983;97:1-67
pubmed: 6306751
Tropenmed Parasitol. 1975 Dec;26(4):385-9
pubmed: 1216327
J Eukaryot Microbiol. 2022 Sep;69(5):e12884
pubmed: 34995386
Indian J Biochem Biophys. 2015 Feb;52(1):14-22
pubmed: 26040107

Auteurs

Alexey V Osipov (AV)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

Elena G Cheremnykh (EG)

Mental Health Research Centre, Moscow 115522, Russia.

Rustam H Ziganshin (RH)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

Vladislav G Starkov (VG)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

Trang Thuy Thi Nguyen (TTT)

Faculty of Pharmacy, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam.

Khoa Cuu Nguyen (KC)

Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 700000, Vietnam.

Dung Tien Le (DT)

Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 700000, Vietnam.

Anh Ngoc Hoang (AN)

Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 700000, Vietnam.

Victor I Tsetlin (VI)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

Yuri N Utkin (YN)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.

Classifications MeSH