Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.
cardiovascular risk
childhood obesity
childhood overweight
dyslipidemia
hyperinsulinemia
hypertension
metabolic syndrome
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
17 Apr 2023
17 Apr 2023
Historique:
received:
13
02
2023
revised:
25
03
2023
accepted:
12
04
2023
medline:
16
5
2023
pubmed:
16
5
2023
entrez:
16
5
2023
Statut:
epublish
Résumé
Metabolic syndrome (MetS) is defined by a cluster of several cardio-metabolic risk factors, specifically visceral obesity, hypertension, dyslipidemia, and impaired glucose metabolism, which together increase risks of developing future cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D). This article is a narrative review of the literature and a summary of the main observations, conclusions, and perspectives raised in the literature and the study projects of the Working Group of Childhood Obesity (WGChO) of the Italian Society of Paediatric Endocrinology and Diabetology (ISPED) on MetS in childhood obesity. Although there is an agreement on the distinctive features of MetS, no international diagnostic criteria in a pediatric population exist. Moreover, to date, the prevalence of MetS in childhood is not certain and thus the true value of diagnosis of MetS in youth as well as its clinical implications, is unclear. The aim of this narrative review is to summarize the pathogenesis and current role of MetS in children and adolescents with particular reference to applicability in clinical practice in childhood obesity.
Identifiants
pubmed: 37189984
pii: children10040735
doi: 10.3390/children10040735
pmc: PMC10136891
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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