Influence of Obesity on Coronary Artery Disease and Clinical Outcomes in the ADVANCE Registry.

Humans Coronary Artery Disease / diagnostic imaging Overweight Fractional Flow Reserve, Myocardial Coronary Angiography / methods Obesity / complications Coronary Stenosis / diagnostic imaging Computed Tomography Angiography Registries Predictive Value of Tests

body mass index coronary artery disease coronary stenosis obesity overweight

Journal

Circulation. Cardiovascular imaging

ISSN: 1942-0080

Titre abrégé: Circ Cardiovasc Imaging

Pays: United States

ID NLM: 101479935

Informations de publication

Date de publication:
05 2023

Historique:

medline: 18 5 2023

pubmed: 16 5 2023

entrez: 16 5 2023

Statut: ppublish

Résumé

The relationship between body size and cardiovascular events is complex. This study utilized the ADVANCE (Assessing Diagnostic Value of Noninvasive FFR The ADVANCE registry enrolled patients undergoing evaluation for clinically suspected CAD who had >30% stenosis on cardiac computed tomography angiography. Patients were stratified by BMI: normal <25 kg/m Among 5014 patients, 2166 (43.2%) had a normal BMI, 1883 (37.6%) were overweight, and 965 (19.2%) were obese. Patients with obesity were younger and more likely to have comorbidities, including diabetes and hypertension (all Patients with obesity in the ADVANCE registry were less likely to have anatomically obstructive CAD by cardiac computed tomography angiography but had a similar degree of physiologically significant CAD by FFR

Sections du résumé

BACKGROUND

The relationship between body size and cardiovascular events is complex. This study utilized the ADVANCE (Assessing Diagnostic Value of Noninvasive FFR

METHODS

The ADVANCE registry enrolled patients undergoing evaluation for clinically suspected CAD who had >30% stenosis on cardiac computed tomography angiography. Patients were stratified by BMI: normal <25 kg/m

RESULTS

Among 5014 patients, 2166 (43.2%) had a normal BMI, 1883 (37.6%) were overweight, and 965 (19.2%) were obese. Patients with obesity were younger and more likely to have comorbidities, including diabetes and hypertension (all

CONCLUSIONS

Patients with obesity in the ADVANCE registry were less likely to have anatomically obstructive CAD by cardiac computed tomography angiography but had a similar degree of physiologically significant CAD by FFR

Identifiants

DOI: 10.1161/CIRCIMAGING.122.014850 PMID: 37192296

pubmed: 37192296

doi: 10.1161/CIRCIMAGING.122.014850

doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

e014850