MiRNA-520a-3p combined with folic acid conjugated Fe
Osteosarcoma
folic acid
gene therapy
magnetic resonance imaging
miR-520a-3p
photothermal therapy
Journal
Nanotechnology
ISSN: 1361-6528
Titre abrégé: Nanotechnology
Pays: England
ID NLM: 101241272
Informations de publication
Date de publication:
29 Jun 2023
29 Jun 2023
Historique:
received:
08
02
2023
accepted:
15
05
2023
medline:
3
7
2023
pubmed:
17
5
2023
entrez:
16
5
2023
Statut:
epublish
Résumé
Osteosarcoma (OS) is a primary malignant bone tumor that occurs mainly in adolescents. Researchers are devoting to develop combination therapy methods in a multifunctional nanoplatform for the treatment of osteosarcoma. The results of previous research have shown that up-regulation of miR-520a-3p could induce anticancer effects in osteosarcoma. In order to improve the effect of gene therapy (GT), we attempted to carry miR-520a-3p in a multifunctional vector for comprehensive therapy. Fe
Identifiants
pubmed: 37192608
doi: 10.1088/1361-6528/acd5d9
doi:
Substances chimiques
MicroRNAs
0
polydopamine
0
Folic Acid
935E97BOY8
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2023 IOP Publishing Ltd.