Adipose Tissue-Derived Stromal/Stem Cells Transplantation with Cholecalciferol Supplementation in Recent-Onset Type 1 Diabetes Patients: Twelve Months Follow-Up.

Humans Diabetes Mellitus, Type 1 / therapy Cholecalciferol / therapeutic use Glycated Hemoglobin Pilot Projects Prospective Studies Follow-Up Studies Insulin / metabolism Adipose Tissue / metabolism Dietary Supplements Stem Cells / metabolism Forkhead Transcription Factors

Journal

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
ISSN: 1439-4286
Titre abrégé: Horm Metab Res
Pays: Germany
ID NLM: 0177722

Informations de publication

Date de publication:
Aug 2023
Historique:
medline: 23 10 2023
pubmed: 17 5 2023
entrez: 16 5 2023
Statut: ppublish

Résumé

To evaluate safety and therapeutic effect along 12 months of allogenic adipose tissue-derived stromal/stem cells (ASCs) transplantation with cholecalciferol (VITD) in patients with recent-onset type 1 diabetes (T1D). Prospective, phase II, open trial, pilot study in which patients with recent onset T1D received ASCs (1xKgx10

Identifiants

DOI: 10.1055/a-2094-1039 PMID: 37192655
pubmed: 37192655
doi: 10.1055/a-2094-1039
doi:

Substances chimiques

Cholecalciferol 1C6V77QF41
Glycated Hemoglobin 0
Insulin 0
Forkhead Transcription Factors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

536-545

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

Auteurs

Joana R Dantas (JR)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Debora Batista Araujo (DB)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Karina Ribeiro Silva (KR)

Laboratory of Tissue Bioengineering, Instituto Nacional de Metrologia Qualidade e Tecnologia Campus de Xerem, Duque de Caxias, Brazil.
Histology and Embryology Departament, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.

Debora Lopes Souto (DL)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Maria de Fatima Carvalho Pereira (MFC)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Luiz Ronir Raggio (LR)

Institute of Public Health Studies, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Cesar Claudio-da Silva (C)

Plastic Surgery, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Carlos Eduardo Couri (CE)

Internal Medicine, Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto, Ribeirao Preto, Brazil.

Angelo Maiolino (A)

Hematology Department, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Carmen Lucia Kuniyoshi Rebellato (CLK)

Core Cell Technology, Pontifical Catholic University of Parana, Curitiba, Brazil.

Debora Regina Daga (DR)

Core Cell Technology, Pontifical Catholic University of Parana, Curitiba, Brazil.

Alexandra Cristina Senegaglia (AC)

Core Cell Technology, Pontifical Catholic University of Parana, Curitiba, Brazil.

Paulo Roberto Slud Brofman (PRS)

Core Cell Technology, Pontifical Catholic University of Parana, Curitiba, Brazil.

Leandra S Baptista (LS)

Laboratory of Tissue Bioengineering, Instituto Nacional de Metrologia Qualidade e Tecnologia Campus de Xerem, Duque de Caxias, Brazil.
Center for Biological Research (Numpex-Bio), Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Jose Egidio Paulo de Oliveira (JEP)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Lenita Zajdenverg (L)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Melanie Rodacki (M)

Nutrology and Diabetes Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Diabète de type 1 › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Lipides › Lipides membranaires › Stérols › Cholécalciférol › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Produits terminaux de glycation avancée › Protéines glyquées › Protéine glycosylée sérique › Hémoglobine glycosylée › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Projets pilotes › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études de suivi › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Aliments et boissons › Aliments › Compléments alimentaires › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Cellules › Cellules souches › Adipose Tissue-Derived Stromal/Stem Cells...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif hélice ailée › Facteurs de transcription Forkhead › Adipose Tissue-Derived Stromal/Stem Cells...