Difficult to think about but easy to treat: scurvy.
gingival hypertrophy
scurvy
vitamin c
Journal
Journal of pediatric endocrinology & metabolism : JPEM
ISSN: 2191-0251
Titre abrégé: J Pediatr Endocrinol Metab
Pays: Germany
ID NLM: 9508900
Informations de publication
Date de publication:
26 Jul 2023
26 Jul 2023
Historique:
received:
23
03
2023
accepted:
26
04
2023
medline:
10
7
2023
pubmed:
17
5
2023
entrez:
16
5
2023
Statut:
epublish
Résumé
Severe vitamin C deficiency, or scurvy, presents as a syndrome of multisystem abnormalities associated with defective collagen synthesis and antioxidative functions. The many clinical features of scurvy lead to frequent misdiagnoses, as they can often point to other diseases, such as vasculitis, venous thrombosis and musculoskeletal disorders. As such, an extensive workup is recommended in cases in which scurvy is suspected. A 21-month-old male patient and a 36-month-old female patient presented with difficulty in walking, painful joint movements, irritability, gingival hypertrophy and bleeding. After exhaustive investigations and risky invasive procedures, vitamin C deficiency was diagnosed in both cases, and the symptoms improved dramatically with vitamin C treatment. The importance of taking a dietary history in pediatric patients is highly recommended. In cases where scurvy is considered, serum ascorbic acid levels should be checked to confirm the diagnosis prior to conducting invasive tests.
Identifiants
pubmed: 37193674
pii: jpem-2023-0129
doi: 10.1515/jpem-2023-0129
doi:
Substances chimiques
Ascorbic Acid
PQ6CK8PD0R
Vitamins
0
Antioxidants
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
708-711Informations de copyright
© 2023 Walter de Gruyter GmbH, Berlin/Boston.
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