Full-Spectrum CARS Microscopy of Cells and Tissues with Ultrashort White-Light Continuum Pulses.


Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
01 06 2023
Historique:
medline: 2 6 2023
pubmed: 17 5 2023
entrez: 17 5 2023
Statut: ppublish

Résumé

Coherent anti-Stokes Raman scattering (CARS) microscopy is an emerging nonlinear vibrational imaging technique that delivers label-free chemical maps of cells and tissues. In narrowband CARS, two spatiotemporally superimposed picosecond pulses, pump and Stokes, illuminate the sample to interrogate a single vibrational mode. Broadband CARS (BCARS) combines narrowband pump pulses with broadband Stokes pulses to record broad vibrational spectra. Despite recent technological advancements, BCARS microscopes still struggle to image biological samples over the entire Raman-active region (400-3100 cm

Identifiants

pubmed: 37195090
doi: 10.1021/acs.jpcb.3c01443
pmc: PMC10240501
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4733-4745

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Auteurs

Federico Vernuccio (F)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Renzo Vanna (R)

CNR-Institute for Photonics and Nanotechnologies (IFN-CNR), Piazza Leonardo Da Vinci 32, 20133 Milan, Italy.

Chiara Ceconello (C)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Arianna Bresci (A)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Francesco Manetti (F)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Salvatore Sorrentino (S)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.

Silvia Ghislanzoni (S)

MALDI-imaging Lab, Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Amadeo 42, 20133, Milan, Italy.

Flavia Lambertucci (F)

Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, 75006 Paris, France.
Metabolomics and Cell Biology Platforms, Gustave Roussy, 94805 Villejuif, France.

Omar Motiño (O)

Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, 75006 Paris, France.
Metabolomics and Cell Biology Platforms, Gustave Roussy, 94805 Villejuif, France.

Isabelle Martins (I)

Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, 75006 Paris, France.
Metabolomics and Cell Biology Platforms, Gustave Roussy, 94805 Villejuif, France.

Guido Kroemer (G)

Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, 75006 Paris, France.
Metabolomics and Cell Biology Platforms, Gustave Roussy, 94805 Villejuif, France.
Institut du Cancer Paris CARPEM, Department of Biology, Hôpital Européen Georges Pompidou HP, 75015 Paris, France.

Italia Bongarzone (I)

MALDI-imaging Lab, Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G. Amadeo 42, 20133, Milan, Italy.

Giulio Cerullo (G)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.
CNR-Institute for Photonics and Nanotechnologies (IFN-CNR), Piazza Leonardo Da Vinci 32, 20133 Milan, Italy.

Dario Polli (D)

Department of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.
CNR-Institute for Photonics and Nanotechnologies (IFN-CNR), Piazza Leonardo Da Vinci 32, 20133 Milan, Italy.

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Classifications MeSH