Risk factors for the long-term incidence and progression of knee osteoarthritis in older adults: role of nonsurgical injury.
chronic disease
joint structural changes
knee arthroplasty
knee injury
osteoarthritis
risk factors
symptoms
Journal
Therapeutic advances in chronic disease
ISSN: 2040-6223
Titre abrégé: Ther Adv Chronic Dis
Pays: United States
ID NLM: 101532140
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
10
2022
accepted:
28
03
2023
pubmed:
18
5
2023
medline:
18
5
2023
entrez:
17
5
2023
Statut:
epublish
Résumé
For one of the most chronic medical conditions, osteoarthritis, uncertainties remain on the impact of injury chronology, the role of repeat injury on the incidence/progression of this disease and the need for knee arthroplasty. To explore, in an older adult population, how nonsurgical knee injuries relate to osteoarthritis incidence/progression and the weight of independent risk factors for arthroplasty. A cohort study design evaluates the long-term impact of injuries on knee osteoarthritis outcomes. Knees with no prior injury ( At inclusion, knees with prior injury demonstrated greater incidence and severity of osteoarthritis ( This study highlights the importance of nonsurgical knee injury in older adults as an independent risk factor for knee osteoarthritis and arthroplasty. These data will be beneficial in clinical practice as they will help identify individuals at greater risk of significant disease progression and worst disease outcomes for a customized therapeutic approach.
Sections du résumé
Background
UNASSIGNED
For one of the most chronic medical conditions, osteoarthritis, uncertainties remain on the impact of injury chronology, the role of repeat injury on the incidence/progression of this disease and the need for knee arthroplasty.
Objectives
UNASSIGNED
To explore, in an older adult population, how nonsurgical knee injuries relate to osteoarthritis incidence/progression and the weight of independent risk factors for arthroplasty.
Design
UNASSIGNED
A cohort study design evaluates the long-term impact of injuries on knee osteoarthritis outcomes.
Methods
UNASSIGNED
Knees with no prior injury (
Results
UNASSIGNED
At inclusion, knees with prior injury demonstrated greater incidence and severity of osteoarthritis (
Conclusion
UNASSIGNED
This study highlights the importance of nonsurgical knee injury in older adults as an independent risk factor for knee osteoarthritis and arthroplasty. These data will be beneficial in clinical practice as they will help identify individuals at greater risk of significant disease progression and worst disease outcomes for a customized therapeutic approach.
Identifiants
pubmed: 37197137
doi: 10.1177/20406223231169715
pii: 10.1177_20406223231169715
pmc: PMC10184209
doi:
Types de publication
Journal Article
Langues
eng
Pagination
20406223231169715Informations de copyright
© The Author(s), 2023.
Déclaration de conflit d'intérêts
The authors declared the following potential conflicts of interest with respect to the research, authorship and/or publication of this article: J.-P.P. and J.M.-P. are shareholders in ArthroLab Inc.