Low seroprotection against diphtheria and tetanus in Lao adolescents.
Laos
diphtheria
seroprevalence
tetanus
vaccination
Journal
Tropical medicine & international health : TM & IH
ISSN: 1365-3156
Titre abrégé: Trop Med Int Health
Pays: England
ID NLM: 9610576
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
medline:
5
6
2023
pubmed:
18
5
2023
entrez:
18
5
2023
Statut:
ppublish
Résumé
There is currently no booster diphtheria or tetanus vaccine for Lao children before adolescence, despite international recommendations. We investigated seroprotection against diphtheria and tetanus among Lao adolescents. Seven hundred seventy-nine serum samples were tested for anti-diphtheria and anti-tetanus antibodies. Overall, 25.8% of the adolescents had antibody titers corresponding to protection against diphtheria and 30.9% to sufficient immunity against tetanus. Female participants >16 years were more likely to be protected against diphtheria (p < 0.001) and tetanus (p < 0.029). Low protection against diphtheria and tetanus, possibly due to low vaccination coverage or antibody waning, suggests booster doses are warranted before adolescence.
Substances chimiques
Antibodies, Bacterial
0
Tetanus Toxoid
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
501-506Informations de copyright
© 2023 The Authors Tropical Medicine & International Health Published by John Wiley & Sons Ltd.
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