Iron deficiency and its epigenetic effects on iron homeostasis.
Epigenetics
Ferroportin
Hepcidin
Iron deficiency
Iron homeostasis
JmjC histone demethylase
Ten eleven translocase
Journal
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
ISSN: 1878-3252
Titre abrégé: J Trace Elem Med Biol
Pays: Germany
ID NLM: 9508274
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
received:
16
02
2022
revised:
27
04
2023
accepted:
14
05
2023
medline:
31
5
2023
pubmed:
19
5
2023
entrez:
18
5
2023
Statut:
ppublish
Résumé
Iron deficiency is a common micronutrient deficiency associated with metabolic changes in the levels of iron regulatory proteins, hepcidin and ferroportin. Studies have associated dysregulation of iron homeostasis to other secondary and life-threatening diseases including anaemia, neurodegeneration and metabolic diseases. Iron deficiency plays a critical role in epigenetic regulation by affecting the Fe
Identifiants
pubmed: 37201368
pii: S0946-672X(23)00079-2
doi: 10.1016/j.jtemb.2023.127203
pii:
doi:
Substances chimiques
Hepcidins
0
Histone Demethylases
EC 1.14.11.-
Iron
E1UOL152H7
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
127203Informations de copyright
Copyright © 2023 Elsevier GmbH. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declared no conflicting interest.