A microphysiological model of bone development and regeneration.

Humans Endothelial Cells Osteogenesis Cartilage / physiology Bone and Bones Organoids Lab-On-A-Chip Devices
bone development microphysiological model organ on chip

Journal

Biofabrication
ISSN: 1758-5090
Titre abrégé: Biofabrication
Pays: England
ID NLM: 101521964

Informations de publication

Date de publication:
06 06 2023
Historique:
received: 01 08 2022
accepted: 18 05 2023
medline: 7 6 2023
pubmed: 19 5 2023
entrez: 18 5 2023
Statut: epublish

Résumé

Endochondral ossification (EO) is an essential biological process than underpins how human bones develop, grow, and heal in the event of a fracture. So much is unknown about this process, thus clinical manifestations of dysregulated EO cannot be adequately treated. This can be partially attributed to the absence of predictive

Identifiants

DOI: 10.1088/1758-5090/acd6be PMID: 37201517
pubmed: 37201517
doi: 10.1088/1758-5090/acd6be
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Creative Commons Attribution license.

Auteurs

Ian T Whelan (IT)

Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
CÚRAM Center for Research in Medical Devices, National University of Ireland, Galway, Ireland.
ORCID: 0000-0002-9005-1439

Ross Burdis (R)

Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

Somayeh Shahreza (S)

Department of Mechanical Engineering, University College London, London, United Kingdom.

Emad Moeendarbary (E)

Department of Mechanical Engineering, University College London, London, United Kingdom.
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, United States of America.
199 Biotechnologies Ltd, Gloucester Road, W2 6LD London, United Kingdom.

David A Hoey (DA)

Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Advanced Materials and Bioengineering Research Centre (AMBER), Royal College of Surgeons in Ireland and Trinity College Dublin, Dublin, Ireland.
Department of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, Dublin, Ireland.
CÚRAM Center for Research in Medical Devices, National University of Ireland, Galway, Ireland.
ORCID: 0000-0001-5898-0409

Daniel J Kelly (DJ)

Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Advanced Materials and Bioengineering Research Centre (AMBER), Royal College of Surgeons in Ireland and Trinity College Dublin, Dublin, Ireland.
Department of Mechanical, Manufacturing and Biomedical Engineering, School of Engineering, Trinity College Dublin, Dublin, Ireland.
CÚRAM Center for Research in Medical Devices, National University of Ireland, Galway, Ireland.
ORCID: 0000-0003-4091-0992

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A microphysiological model of bone development...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › A microphysiological model of bone development...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Développement locomoteur › Biominéralisation › Développement osseux › Ostéogenèse › A microphysiological model of bone development...
questionsmedicales.fr › Tissus › Tissu conjonctif › Cartilage › A microphysiological model of bone development...
questionsmedicales.fr › Tissus › Tissu conjonctif › Os et tissu osseux › A microphysiological model of bone development...
questionsmedicales.fr › Tissus › Organoïdes › A microphysiological model of bone development...
questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures électriques › Laboratoires sur puces › A microphysiological model of bone development...