Dural Tail Sign and Middle Meningeal Artery Hypertrophy in Glioblastoma: A Rarity?


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 15 04 2023
accepted: 09 05 2023
medline: 9 8 2023
pubmed: 19 5 2023
entrez: 18 5 2023
Statut: ppublish

Résumé

Dural tail sign and increased caliber of branches of the external carotid artery (ECA) are common findings in meningioma and they have been rarely reported in intra-axial lesions. Anyway, some cases of glioblastoma (GBM) are reported in the literature, mostly superficially localized, characterized by these 2 findings and therefore, misdiagnosed with meningioma. The aim of this study is to verify the prevalence of dural tail sign and hypertrophy of middle meningeal artery (MMA) in a large cohort of GBMs. 180 GBM patients were retrospectively evaluated. Deep or superficial localization of GBM was established and the presence of dural tail sign and hypertrophy of the ipsilateral MMA were assessed. The rate of tumor necrosis and the incidence of dural metastases during the radiological follow-up were also evaluated. Inter-rater reliability was calculated using Cohen's K-test. Dural tail sign and enlarged MMA were evident in 30% and 19% of 96 superficial GBM, respectively. Deep GBM did not present those signs. Only one patient developed dural metastasis at follow-up and no differences in terms of tumor necrosis and hypoxic biomarkers expression were evident among GBMs with and without dural and vessel signs. Dural tail sign and hypertrophy of the MMA in superficial GBM are more common than expected. They probably represent reactive rather than a neoplastic infiltration. Knowing these radiological signs may be important in terms of neurosurgery planning and avoiding excessive bleeding. Anyway, this hypothesis should be confirmed by a prospective neurosurgery studio.

Sections du résumé

BACKGROUND BACKGROUND
Dural tail sign and increased caliber of branches of the external carotid artery (ECA) are common findings in meningioma and they have been rarely reported in intra-axial lesions. Anyway, some cases of glioblastoma (GBM) are reported in the literature, mostly superficially localized, characterized by these 2 findings and therefore, misdiagnosed with meningioma. The aim of this study is to verify the prevalence of dural tail sign and hypertrophy of middle meningeal artery (MMA) in a large cohort of GBMs.
METHODS METHODS
180 GBM patients were retrospectively evaluated. Deep or superficial localization of GBM was established and the presence of dural tail sign and hypertrophy of the ipsilateral MMA were assessed. The rate of tumor necrosis and the incidence of dural metastases during the radiological follow-up were also evaluated. Inter-rater reliability was calculated using Cohen's K-test.
RESULTS RESULTS
Dural tail sign and enlarged MMA were evident in 30% and 19% of 96 superficial GBM, respectively. Deep GBM did not present those signs. Only one patient developed dural metastasis at follow-up and no differences in terms of tumor necrosis and hypoxic biomarkers expression were evident among GBMs with and without dural and vessel signs.
CONCLUSIONS CONCLUSIONS
Dural tail sign and hypertrophy of the MMA in superficial GBM are more common than expected. They probably represent reactive rather than a neoplastic infiltration. Knowing these radiological signs may be important in terms of neurosurgery planning and avoiding excessive bleeding. Anyway, this hypothesis should be confirmed by a prospective neurosurgery studio.

Identifiants

pubmed: 37201790
pii: S1878-8750(23)00647-2
doi: 10.1016/j.wneu.2023.05.038
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e240-e245

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Andrea Romano (A)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

Giulia Moltoni (G)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy. Electronic address: giulia.moltoni@uniroma1.it.

Francesco Dellepiane (F)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

Serena Palizzi (S)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

Allegra Romano (A)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

Alessia Guarnera (A)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

Antonella Stoppacciaro (A)

Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University Sapienza, Rome, Italy.

Michele Aqui (M)

NESMOS, Department of Neurosurgery, S.Andrea Hospital, University Sapienza, Rome, Italy; Department of Neurosurgery, University Hospital of Udine, Udine, Italy.

Tamara Ius (T)

NESMOS, Department of Neurosurgery, S.Andrea Hospital, University Sapienza, Rome, Italy.

Massimo Miscusi (M)

NESMOS, Department of Neurosurgery, S.Andrea Hospital, University Sapienza, Rome, Italy.

Antonino Raco (A)

NESMOS, Department of Neurosurgery, S.Andrea Hospital, University Sapienza, Rome, Italy.

Alessandro Bozzao (A)

NESMOS, Department of Neuroradiology, S.Andrea Hospital, University Sapienza, Rome, Italy.

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