SARS-CoV2 in public spaces in West London, UK during COVID-19 pandemic.


Journal

BMJ open respiratory research
ISSN: 2052-4439
Titre abrégé: BMJ Open Respir Res
Pays: England
ID NLM: 101638061

Informations de publication

Date de publication:
05 2023
Historique:
received: 02 12 2022
accepted: 28 04 2023
medline: 22 5 2023
pubmed: 19 5 2023
entrez: 18 5 2023
Statut: ppublish

Résumé

Spread of SARS-CoV2 by aerosol is considered an important mode of transmission over distances >2 m, particularly indoors. We determined whether SARS-CoV2 could be detected in the air of enclosed/semi-enclosed public spaces. Between March 2021 and December 2021 during the easing of COVID-19 pandemic restrictions after a period of lockdown, we used total suspended and size-segregated particulate matter (PM) samplers for the detection of SARS-CoV2 in hospitals wards and waiting areas, on public transport, in a university campus and in a primary school in West London. We collected 207 samples, of which 20 (9.7%) were positive for SARS-CoV2 using quantitative PCR. Positive samples were collected from hospital patient waiting areas, from hospital wards treating patients with COVID-19 using stationary samplers and from train carriages in London underground using personal samplers. Mean virus concentrations varied between 429 500 copies/m During a period of partial opening during the COVID-19 pandemic in London, we detected SARS-CoV2 RNA in the air of hospital waiting areas and wards and of London Underground train carriage. More research is needed to determine the transmission potential of SARS-CoV2 detected in the air.

Sections du résumé

BACKGROUND
Spread of SARS-CoV2 by aerosol is considered an important mode of transmission over distances >2 m, particularly indoors.
OBJECTIVES
We determined whether SARS-CoV2 could be detected in the air of enclosed/semi-enclosed public spaces.
METHODS AND ANALYSIS
Between March 2021 and December 2021 during the easing of COVID-19 pandemic restrictions after a period of lockdown, we used total suspended and size-segregated particulate matter (PM) samplers for the detection of SARS-CoV2 in hospitals wards and waiting areas, on public transport, in a university campus and in a primary school in West London.
RESULTS
We collected 207 samples, of which 20 (9.7%) were positive for SARS-CoV2 using quantitative PCR. Positive samples were collected from hospital patient waiting areas, from hospital wards treating patients with COVID-19 using stationary samplers and from train carriages in London underground using personal samplers. Mean virus concentrations varied between 429 500 copies/m
CONCLUSION
During a period of partial opening during the COVID-19 pandemic in London, we detected SARS-CoV2 RNA in the air of hospital waiting areas and wards and of London Underground train carriage. More research is needed to determine the transmission potential of SARS-CoV2 detected in the air.

Identifiants

pubmed: 37202121
pii: 10/1/e001574
doi: 10.1136/bmjresp-2022-001574
pmc: PMC10200905
pii:
doi:

Substances chimiques

RNA, Viral 0
Particulate Matter 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/disclosure-of-interest/ and declare: support from UKRI EPSRC COVID-19 rapid response grant number EP/V052462/1 for the submitted; no financial relationships with any organisations that might have an interest in the submitted work in the previous 3 years; no other relationships or activities that could appear to have influenced the submitted work.

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Auteurs

Hisham Abubakar-Waziri (H)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Gopinath Kalaiarasan (G)

Department of Civil and Environmental Engineering, Global Centre for Clean Air Research, Surrey, UK.

Rebecca Wawman (R)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Faye Hobbs (F)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Ian Adcock (I)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Claire Dilliway (C)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Fangxin Fang (F)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Christopher Pain (C)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Alexandra Porter (A)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Pankaj K Bhavsar (PK)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Emma Ransome (E)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Vincent Savolainen (V)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK.

Prashant Kumar (P)

Department of Civil and Environmental Engineering, Global Centre for Clean Air Research, Surrey, UK.

Kian Fan Chung (KF)

Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK f.chung@imperial.ac.uk.

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