Crosslinking for post-laser-assisted
Male
Female
Humans
Keratomileusis, Laser In Situ
/ adverse effects
Keratoconus
/ diagnosis
Photosensitizing Agents
/ therapeutic use
Dilatation, Pathologic
/ diagnosis
Riboflavin
/ therapeutic use
Corneal Topography
Cross-Linking Reagents
/ therapeutic use
Collagen
/ therapeutic use
Lasers
Ultraviolet Rays
Photochemotherapy
/ methods
Crosslinking
LASIK
ectasia
treatment
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
05 2023
05 2023
Historique:
medline:
22
5
2023
pubmed:
19
5
2023
entrez:
19
5
2023
Statut:
ppublish
Résumé
To evaluate the outcomes of transepithelial corneal collagen crosslinking (CXL) for management of corneal ectasia after laser-assisted in situ keratomileusis (LASIK). CXL was performed on 18 eyes of 16 patients either with LASIK flap lift (n = 9; 365 nm, 30 mW/cm A total of 18 eyes of 16 patients (11 males, 5 females) were included. Overall, Kmax flattened more after flap-on CXL (P = 0.014) compared to flap-lift CXL. The endothelial cell density and posterior elevation were stable throughout the follow-up period. Index of vertical asymmetry (IVA), keratoconus index (KI), and central keratoconus index (CKI) decreased after flap-on CXL at 12 months, postoperatively (P < 0.05), whereas there were no statistically significant changes in these parameters after flap-off CXL group. The spherical aberrations and total root mean square decreased after flap-lift CXL at 12 months, postoperatively (P < 0.05). In our study, transepithelial collagen crosslinking was successfully used to halt disease progression in post-LASIK keratectasia. We recommend flap-on surgical technique for these cases.
Identifiants
pubmed: 37203051
pii: IndianJOphthalmol_2023_71_5_1894_377008
doi: 10.4103/IJO.IJO_2633_22
pmc: PMC10391513
doi:
Substances chimiques
Photosensitizing Agents
0
Riboflavin
TLM2976OFR
Cross-Linking Reagents
0
Collagen
9007-34-5
Types de publication
Journal Article
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
1894-1898Commentaires et corrections
Type : CommentOn
Déclaration de conflit d'intérêts
None
Références
Am J Ophthalmol. 2003 May;135(5):620-7
pubmed: 12719068
J Cataract Refract Surg. 2016 May;42(5):738-49
pubmed: 27255251
Ophthalmology. 2003 Feb;110(2):267-75
pubmed: 12578766
Ophthalmology. 2013 Jul;120(7):1354-9
pubmed: 23582990
Cornea. 2006 Aug;25(7):845-8
pubmed: 17068463
Asia Pac J Ophthalmol (Phila). 2015 Sep-Oct;4(5):300-6
pubmed: 26381468
Am J Ophthalmol. 2015 Dec;160(6):1154-63
pubmed: 26307513
J Refract Surg. 2008 Sep;24(7):S720-5
pubmed: 18811118
Sci Rep. 2015 Sep 25;5:14425
pubmed: 26404661
Int Ophthalmol Clin. 2008 Winter;48(1):73-81
pubmed: 18209559
Eur J Ophthalmol. 2013 Nov-Dec;23(6):799-806
pubmed: 23787452
Am J Ophthalmol. 2015 May;159(5):821-8.e3
pubmed: 25703475
J Cataract Refract Surg. 2015 Sep;41(9):2014-8
pubmed: 26603410
Asia Pac J Ophthalmol (Phila). 2017 May-Jun;6(3):228-232
pubmed: 28379654