Genomic variation during culture adaptation of genetically complex


Journal

Microbial genomics
ISSN: 2057-5858
Titre abrégé: Microb Genom
Pays: England
ID NLM: 101671820

Informations de publication

Date de publication:
05 2023
Historique:
medline: 22 5 2023
pubmed: 19 5 2023
entrez: 19 5 2023
Statut: ppublish

Résumé

Experimental studies on the biology of malaria parasites have mostly been based on laboratory-adapted lines, but there is limited understanding of how these may differ from parasites in natural infections. Loss-of-function mutants have previously been shown to emerge during culture of some

Identifiants

pubmed: 37204422
doi: 10.1099/mgen.0.001009
pmc: PMC10272863
doi:

Substances chimiques

Guanine Nucleotide Exchange Factors 0
SRPK1 protein, human EC 2.7.1.-
Protein Serine-Threonine Kinases EC 2.7.11.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
ID : 206194
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 090770
Pays : United Kingdom
Organisme : Medical Research Council
ID : G1100123
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 098051
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S009760/1
Pays : United Kingdom

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Auteurs

Antoine Claessens (A)

LPHI, MIVEGEC, INSERM, CNRS, IRD, University of Montpellier, France.
Department of Infection Biology, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.

Lindsay B Stewart (LB)

Department of Infection Biology, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.

Eleanor Drury (E)

Wellcome Sanger Institute, Cambridge, CB10 1SA, UK.

Ambroise D Ahouidi (AD)

Le Dantec Hospital, Université Cheikh Anta Diop, Dakar, Senegal.

Alfred Amambua-Ngwa (A)

MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.

Mahamadou Diakite (M)

Malaria Research and Training Center, University of Bamako, Bamako, Mali.

Dominic P Kwiatkowski (DP)

Wellcome Sanger Institute, Cambridge, CB10 1SA, UK.

Gordon A Awandare (GA)

West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Ghana.

David J Conway (DJ)

Department of Infection Biology, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.

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Classifications MeSH