Birdshot Chorioretinitis in Patients Aged 80 and Older.

Birdshot chorioretinitis choroid immunosuppressive therapy long-term posterior uveitis

Journal

Ocular immunology and inflammation
ISSN: 1744-5078
Titre abrégé: Ocul Immunol Inflamm
Pays: England
ID NLM: 9312169

Informations de publication

Date de publication:
19 May 2023
Historique:
medline: 19 5 2023
pubmed: 19 5 2023
entrez: 19 5 2023
Statut: aheadofprint

Résumé

To assess the manifestations of birdshot chorioretinitis (BSCR) in patients aged 80 and over. Among patients with BSCR followed in the CO-BIRD prospective cohort (ClinicalTrials.gov Identifier: NCT05153057), we analyzed the subgroup of patients aged 80 and over. Patients were assessed in a standardized manner. Confluent atrophy was defined as hypoautofluorescent spots on fundus autofluorescence (FAF). We included 39 (8.8%) of the 442 enrolled CO-BIRD patients. The mean age was 83.8 ± 3.7 years. The mean logMAR BCVA was 0.52 ± 0.76, with 30 patients (76.9%) having 20/40 or better in at least one eye. Thirty-five (89.7%) patients were receiving no treatment. Confluent atrophy in the posterior pole, disrupted retrofoveal ellipsoid zone and choroidal neovascularization were associated with logMAR BCVA >0.3 ( In patients aged 80 and over we observed a striking heterogeneity of outcomes, but most retained a BCVA that allowed them to drive.

Identifiants

pubmed: 37204866
doi: 10.1080/09273948.2023.2215322
doi:

Banques de données

ClinicalTrials.gov
['NCT05153057']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-6

Auteurs

Louis Debillon (L)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Jennifer E Thorne (JE)

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Elodie Bousquet (E)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Pierre Duraffour (P)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Souhila Kecili (S)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Dominique Monnet (D)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Antoine P Brézin (AP)

Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.

Classifications MeSH