Biochemical characterization of an acetylesterase from

7-ACA D-7-ACA acetylesterase deacetylation esterase

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2023
Historique:
received: 13 02 2023
accepted: 30 03 2023
medline: 19 5 2023
pubmed: 19 5 2023
entrez: 19 5 2023
Statut: epublish

Résumé

Deacetyl-7-aminocephalosporanic acid (D-7-ACA), which could be converted from 7-aminocephalosporanic acid (7-ACA), is a crucial starting material that is used for synthesizing industrial semisynthetic β-lactam antibiotics. Enzymes involved in the conversion from 7-ACA to D-7-ACA present critical resources in the pharmaceutical industry. In the present study, a putative acetylesterase, EstSJ, identified from

Identifiants

pubmed: 37206334
doi: 10.3389/fmicb.2023.1164815
pmc: PMC10189120
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1164815

Informations de copyright

Copyright © 2023 Wang, Nong, Li, Liu, Wu, Huang, Xu and Ding.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Xiaoliang Wang (X)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Sujin Nong (S)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Jiayi Li (J)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Yan Liu (Y)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Qian Wu (Q)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Zunxi Huang (Z)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Bo Xu (B)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Junmei Ding (J)

Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, Yunnan Normal University, Kunming, China.

Classifications MeSH