Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease.

budesonide children eosinophilic esophagitis esophageal ulcer hematemesis upper GI bleeding

Journal

JPGN reports
ISSN: 2691-171X
Titre abrégé: JPGN Rep
Pays: United States
ID NLM: 101773885

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 23 07 2020
accepted: 08 09 2020
medline: 11 11 2020
pubmed: 11 11 2020
entrez: 19 5 2023
Statut: epublish

Résumé

Gastrointestinal bleeding is a rare but potentially life-threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were subsequently diagnosed with EGID. Accompanying allergic history, peripheral eosinophilia, and total IgE elevation were common. Despite a more severe presentation, response to medical and dietary therapy was favorable. A comprehensive review of the literature revealed 26 other cases with similar findings that reinforced the importance of prompt recognition and early dietary and immunomodulating therapy in the control of this disease.

Identifiants

pubmed: 37206599
doi: 10.1097/PG9.0000000000000017
pmc: PMC10191568
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e017

Informations de copyright

Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors report no funding or conflicts of interest.

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Auteurs

Elif Ozdogan (E)

From the Department of Pediatric Gastroenterology, Hepatology and Nutrition, Koc University School of Medicine, Istanbul, Turkey.

Latife Doganay Caglayan (LD)

Department of Pathology, Kent Hospital, Izmir, Turkey.

Ozlem Mizikoglu (O)

Organ Transplantation Center, Liver Transplantation, Koc University School of Medicine, Istanbul, Turkey.

Cigdem Arikan (C)

From the Department of Pediatric Gastroenterology, Hepatology and Nutrition, Koc University School of Medicine, Istanbul, Turkey.
Organ Transplantation Center, Liver Transplantation, Koc University School of Medicine, Istanbul, Turkey.
Research Center for Translational Medicine (KUTTAM), Koc University, Istanbul, Turkey.

Classifications MeSH