Imbalance of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells in adult patients with primary immune thrombocytopenia.
Primary immune thrombocytopenia
cytokines
follicular helper T (Tfh) cells
follicular regulatory T (Tfr) cells
transcription factors
Journal
Experimental biology and medicine (Maywood, N.J.)
ISSN: 1535-3699
Titre abrégé: Exp Biol Med (Maywood)
Pays: England
ID NLM: 100973463
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
medline:
27
9
2023
pubmed:
20
5
2023
entrez:
20
5
2023
Statut:
ppublish
Résumé
This study is to investigate the role of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells imbalance in adult patients with primary immune thrombocytopenia (ITP). Totally, 40 cases of primary ITP patients and 30 healthy controls were enrolled. Blood samples were collected from ITP patients (pre- and post-therapy) and controls. Flow cytometry was used to detect the proportion of Tfr and Tfh cells in peripheral blood. Real-time quantitative polymerase chain reaction (PCR) was performed to detect the mRNA expression levels of
Identifiants
pubmed: 37208911
doi: 10.1177/15353702231168142
pmc: PMC10525409
doi:
Substances chimiques
Interleukin-10
130068-27-8
RNA, Messenger
0
Forkhead Transcription Factors
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
959-965Références
J Autoimmun. 2019 May;99:1-14
pubmed: 30773373
Exp Ther Med. 2018 Sep;16(3):2471-2477
pubmed: 30186484
Front Immunol. 2020 Feb 14;11:104
pubmed: 32117258
Front Immunol. 2018 Oct 25;9:2469
pubmed: 30410492
Blood. 2014 Oct 30;124(18):2858-66
pubmed: 25232056
Clin Immunol. 2016 Dec;173:161-170
pubmed: 27818202
Front Immunol. 2022 Apr 01;13:810620
pubmed: 35450072
Clin Sci (Lond). 2017 Dec 8;131(24):2933-2945
pubmed: 29109300
J Exp Med. 2015 Sep 21;212(10):1603-21
pubmed: 26371185
Blood Cells Mol Dis. 2016 Oct;61:26-36
pubmed: 27667163
J Clin Lab Anal. 2022 Aug;36(8):e24573
pubmed: 35808925
Blood Adv. 2019 Nov 26;3(22):3780-3817
pubmed: 31770441
Cell Immunol. 2015 May;295(1):46-51
pubmed: 25748125
J Autoimmun. 2017 Feb;77:89-95
pubmed: 27863820
Ann Rheum Dis. 2019 Apr;78(4):539-550
pubmed: 30760472
Blood Adv. 2019 Dec 10;3(23):3829-3866
pubmed: 31794604
Exp Hematol Oncol. 2021 Mar 15;10(1):21
pubmed: 33722280
Eur J Haematol. 2018 Jan;100(1):45-52
pubmed: 28960473
Int J Biol Sci. 2019 Oct 23;15(13):2798-2814
pubmed: 31853219
J Immunol. 2017 Apr 1;198(7):2578-2588
pubmed: 28219887
Int J Lab Hematol. 2021 Oct;43(5):1104-1109
pubmed: 33759370
Nat Immunol. 2015 Mar;16(3):296-305
pubmed: 25642821
Cell Immunol. 2020 May;351:104096
pubmed: 32199587
Autoimmun Rev. 2017 Jun;16(6):620-632
pubmed: 28428120
Front Immunol. 2022 Sep 02;13:928359
pubmed: 36119056
Arthritis Rheumatol. 2015 Apr;67(4):988-99
pubmed: 25581113
Front Pharmacol. 2021 Jan 26;11:587445
pubmed: 33584264
Clin Exp Immunol. 2017 Nov;190(2):201-207
pubmed: 28671717
Scand J Immunol. 2017 Dec;86(6):452-461
pubmed: 28941291
Immunol Res. 2015 Mar;61(3):269-80
pubmed: 25550089
Blood. 2020 Feb 13;135(7):472-490
pubmed: 31756253
Immunol Rev. 2016 May;271(1):246-59
pubmed: 27088919
Trends Immunol. 2015 Jul;36(7):410-8
pubmed: 26091728
Int Immunol. 2016 Apr;28(4):173-9
pubmed: 26714592
J Biomed Sci. 2017 Jul 21;24(1):49
pubmed: 28732506
J Exp Med. 2019 Aug 5;216(8):1843-1856
pubmed: 31209070
Clin Exp Med. 2019 Feb;19(1):55-64
pubmed: 30284646
J Exp Med. 2019 Mar 4;216(3):605-620
pubmed: 30705058
Signal Transduct Target Ther. 2021 Sep 14;6(1):341
pubmed: 34521812
Immunity. 2019 Sep 17;51(3):465-478.e6
pubmed: 31422869
Cell Rep. 2015 Jul 14;12(2):163-71
pubmed: 26146074
Int J Biol Sci. 2015 Jan 05;11(2):220-9
pubmed: 25561904