Progressive and regressive infection with feline leukemia virus (FeLV) in cats in southern Brazil: Prevalence, risk factors associated, clinical and hematologic alterations.
Epidemiology
Feline
Retrovirus
South America
Viral disease
Journal
Preventive veterinary medicine
ISSN: 1873-1716
Titre abrégé: Prev Vet Med
Pays: Netherlands
ID NLM: 8217463
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
received:
04
09
2022
revised:
11
05
2023
accepted:
16
05
2023
medline:
9
6
2023
pubmed:
21
5
2023
entrez:
20
5
2023
Statut:
ppublish
Résumé
Enzyme-linked immunosorbent assay (ELISA) for viral antigen is commonly used for the diagnosis of progressive feline leukemia virus (FeLV) infection but is not able to determine the true prevalence of infection when used as the sole test. Additional testing to detect proviral DNA will identify regressive (antigen negative) FeLV infections as well as progressive infections. Therefore, this study aimed to determine the prevalence of progressive and regressive FeLV infection, outcome-associated factors, and hematologic changes. A cross-sectional study was performed on 384 cats selected from routine hospital care. Blood samples were subjected to complete blood count, ELISA for FeLV antigen and FIV antibody, and nested PCR amplifying the U3- LTR region and gag gene, which are conserved in most exogenous FeLV. The prevalence of FeLV infection was 45.6% (CI
Identifiants
pubmed: 37209619
pii: S0167-5877(23)00109-5
doi: 10.1016/j.prevetmed.2023.105945
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105945Informations de copyright
Copyright © 2023. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None.