A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.

Genetic Map Heterogeneous Stock Hybrid Rat Diversity Panel Inbred Strains Phylogenetic Tree Rat Recombinant Inbred Reference Genome Rnor_6.0 mRatBN7.2

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
28 Sep 2023
Historique:
pubmed: 22 5 2023
medline: 22 5 2023
entrez: 22 5 2023
Statut: epublish

Résumé

The seventh iteration of the reference genome assembly for

Identifiants

DOI: 10.1101/2023.04.13.536694 PMID: 37214860 PMC: PMC10197727
pubmed: 37214860
doi: 10.1101/2023.04.13.536694
pmc: PMC10197727
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM140287
Pays : United States
Organisme : NHLBI NIH HHS
ID : P01 HL149620
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA043098
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL064541
Pays : United States
Organisme : NIAAA NIH HHS
ID : R24 AA013162
Pays : United States
Organisme : NHGRI NIH HHS
ID : U24 HG010859
Pays : United States
Organisme : NIDDK NIH HHS
ID : R21 DK089417
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL089895
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG011252
Pays : United States
Organisme : NIDA NIH HHS
ID : P30 DA044223
Pays : United States
Organisme : NIH HHS
ID : R24 OD024617
Pays : United States
Organisme : NIDA NIH HHS
ID : P50 DA037844
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA051972
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA050239
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA048017
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA047638
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051234
Pays : United States

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Tristan V de Jong (TV)

Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, TN, USA.

Yanchao Pan (Y)

Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.

Pasi Rastas (P)

Institute of Biotechnology, University of Helsinki, Helsinki, Finland.

Daniel Munro (D)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
Department of Integrative Structural and Computational Biology, Scripps Research, San Diego, CA, USA.

Monika Tutaj (M)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA.

Huda Akil (H)

Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.

Chris Benner (C)

Department of Medicine, University of California San Diego, San Diego, CA, USA.

Denghui Chen (D)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

Apurva S Chitre (AS)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

William Chow (W)

Tree of Life, Wellcome Sanger Institute, Cambridge, UK.

Vincenza Colonna (V)

Institute of Genetics and Biophysics, National Research Council, Naples, Italy.
Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Clifton L Dalgard (CL)

Department of Anatomy, Physiology & Genetics; The American Genome Center, Uniformed Services University of the Health Sciences, Washington DC, USA.

Wendy M Demos (WM)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA.

Peter A Doris (PA)

The Brown Foundation Institute of Molecular Medicine, Center For Human Genetics, University of Texas Health Science Center, Houston, TX, USA.

Erik Garrison (E)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Aron M Geurts (AM)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.

Hakan M Gunturkun (HM)

Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, TN, USA.

Victor Guryev (V)

Genome Structure and Ageing, University of Groningen, UMC Groningen, The Netherlands.

Thibaut Hourlier (T)

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus in Hinxton, Cambridgeshire, UK.

Kerstin Howe (K)

Tree of Life, Wellcome Sanger Institute, Cambridge, UK.

Jun Huang (J)

Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, TN, USA.

Ted Kalbfleisch (T)

Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Louisville, KY, USA.

Panjun Kim (P)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Ling Li (L)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.
Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.

Spencer Mahaffey (S)

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Fergal J Martin (FJ)

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus in Hinxton, Cambridgeshire, UK.

Pejman Mohammadi (P)

Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA, USA.
Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.

Ayse Bilge Ozel (AB)

Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.

Oksana Polesskaya (O)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

Michal Pravenec (M)

Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.

Pjotr Prins (P)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Jonathan Sebat (J)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

Jennifer R Smith (JR)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA.

Leah C Solberg Woods (LC)

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Boris Tabakoff (B)

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Alan Tracey (A)

Tree of Life, Wellcome Sanger Institute, Cambridge, UK.

Marcela Uliano-Silva (M)

Tree of Life, Wellcome Sanger Institute, Cambridge, UK.

Flavia Villani (F)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Hongyang Wang (H)

Department of Animal Sciences, Washington State University, Pullman, WA, USA.

Burt M Sharp (BM)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Francesca Telese (F)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

Zhihua Jiang (Z)

Department of Animal Sciences, Washington State University, Pullman, WA, USA.

Laura Saba (L)

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Xusheng Wang (X)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.
Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN, USA.

Terence D Murphy (TD)

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

Abraham A Palmer (AA)

Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.

Anne E Kwitek (AE)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA.

Melinda R Dwinell (MR)

Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Rat Genome Database, Medical College of Wisconsin, Milwaukee, WI, USA.

Robert W Williams (RW)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Jun Z Li (JZ)

Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.

Hao Chen (H)

Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, Memphis, TN, USA.

Classifications MeSH