The Language Network Is Recruited but Not Required for Nonverbal Event Semantics.
aphasia
events
fMRI
language and thought
semantics
thematic roles
Journal
Neurobiology of language (Cambridge, Mass.)
ISSN: 2641-4368
Titre abrégé: Neurobiol Lang (Camb)
Pays: United States
ID NLM: 101763589
Informations de publication
Date de publication:
2021
2021
Historique:
received:
04
09
2020
accepted:
07
01
2021
medline:
17
3
2021
pubmed:
17
3
2021
entrez:
22
5
2023
Statut:
epublish
Résumé
The ability to combine individual concepts of objects, properties, and actions into complex representations of the world is often associated with language. Yet combinatorial event-level representations can also be constructed from nonverbal input, such as visual scenes. Here, we test whether the language network in the human brain is involved in and necessary for semantic processing of events presented nonverbally. In Experiment 1, we scanned participants with fMRI while they performed a semantic plausibility judgment task versus a difficult perceptual control task on sentences and line drawings that describe/depict simple agent-patient interactions. We found that the language network responded robustly during the semantic task performed on both sentences and pictures (although its response to sentences was stronger). Thus, language regions in healthy adults are engaged during a semantic task performed on pictorial depictions of events. But is this engagement necessary? In Experiment 2, we tested two individuals with global aphasia, who have sustained massive damage to perisylvian language areas and display severe language difficulties, against a group of age-matched control participants. Individuals with aphasia were severely impaired on the task of matching sentences to pictures. However, they performed close to controls in assessing the plausibility of pictorial depictions of agent-patient interactions. Overall, our results indicate that the left frontotemporal language network is recruited but not necessary for semantic processing of nonverbally presented events.
Identifiants
pubmed: 37216147
doi: 10.1162/nol_a_00030
pii: nol_a_00030
pmc: PMC10158592
doi:
Types de publication
Journal Article
Langues
eng
Pagination
176-201Informations de copyright
© 2021 Massachusetts Institute of Technology.
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interests exist.
Références
Nat Rev Neurosci. 2003 Apr;4(4):310-22
pubmed: 12671647
J Cogn Neurosci. 2020 Apr;32(4):571-589
pubmed: 31765602
Proc Natl Acad Sci U S A. 2011 May 17;108(20):8520-4
pubmed: 21540329
Psychon Bull Rev. 2013 Jun;20(3):542-50
pubmed: 23307559
PLoS One. 2014 Nov 26;9(11):e112575
pubmed: 25426840
Cortex. 2004 Sep-Dec;40(4-5):631-44
pubmed: 15505973
Cortex. 2011 May;47(5):575-87
pubmed: 20074721
Nat Rev Neurosci. 2008 Dec;9(12):920-33
pubmed: 19020511
Brain. 2010 Nov;133(11):3243-55
pubmed: 20952378
Elife. 2020 Dec 15;9:
pubmed: 33319744
Neuropsychologia. 1999 Sep;37(10):1189-99
pubmed: 10509840
Neuroimage. 2012 May 1;60(4):2357-64
pubmed: 22398396
Cereb Cortex. 2020 May 18;30(6):3838-3855
pubmed: 32279078
Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3519-24
pubmed: 15713804
Brain. 2006 Aug;129(Pt 8):2132-47
pubmed: 16815878
Brain Lang. 1981 Nov;14(2):371-85
pubmed: 7306789
Neuropsychologia. 2017 Oct;105:39-49
pubmed: 28476573
Cognition. 2008 Jul;108(1):155-84
pubmed: 18395705
Cogn Psychol. 2015 May;78:1-27
pubmed: 25791750
J Neurophysiol. 2018 Nov 1;120(5):2555-2570
pubmed: 30156457
Neurology. 2003 Nov 11;61(9):1196-203
pubmed: 14610120
J Exp Psychol Gen. 2003 Jun;132(2):202-27
pubmed: 12825637
Top Cogn Sci. 2020 Jan;12(1):352-386
pubmed: 30963724
Behav Brain Sci. 1999 Apr;22(2):253-79; discussion 280-336
pubmed: 11301524
Cogn Neuropsychol. 2016 May-Jun;33(3-4):257-64
pubmed: 27314175
Brain Lang. 1997 Jun 15;58(2):203-32
pubmed: 9182748
Brain Lang. 2004 Jun;89(3):417-32
pubmed: 15120534
Science. 2002 Nov 22;298(5598):1569-79
pubmed: 12446899
Neuroimage. 2012 Nov 15;63(3):1646-69
pubmed: 22784644
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16428-33
pubmed: 21885736
Cereb Cortex. 2019 Dec 17;29(11):4803-4817
pubmed: 30767007
J Neurophysiol. 2010 Aug;104(2):1177-94
pubmed: 20410363
Dev Sci. 2007 Jan;10(1):89-96
pubmed: 17181705
Cereb Cortex. 2009 Dec;19(12):2767-96
pubmed: 19329570
Cognition. 1991 Dec;41(1-3):1-7
pubmed: 1790651
Nat Commun. 2019 Jan 17;10(1):289
pubmed: 30655531
Nature. 2016 Apr 28;532(7600):453-8
pubmed: 27121839
Neuroimage. 2017 Feb 15;147:952-959
pubmed: 27729277
Neuropsychologia. 2019 Sep;132:107132
pubmed: 31276684
Elife. 2020 Dec 15;9:
pubmed: 33319745
Neuron. 2017 Aug 2;95(3):709-721.e5
pubmed: 28772125
Hum Brain Mapp. 2002 Jul;16(3):168-75
pubmed: 12112770
Perspect Psychol Sci. 2009 Mar;4(2):177-84
pubmed: 20161142
Neuroimage. 2019 Apr 1;189:19-31
pubmed: 30611876
Behav Res Methods Instrum Comput. 2003 Feb;35(1):116-24
pubmed: 12723786
Psychol Sci. 2012 Aug 1;23(8):914-22
pubmed: 22760883
Brain. 2003 Apr;126(Pt 4):928-45
pubmed: 12615649
Psychon Bull Rev. 2007 Aug;14(4):710-6
pubmed: 17972738
Neuropsychologia. 2020 Feb 17;138:107307
pubmed: 31874149
J Neurosci. 2018 Mar 28;38(13):3303-3317
pubmed: 29476016
Neuroimage. 2012 Jan 16;59(2):1369-81
pubmed: 21875671
J Neurosci. 2013 Nov 27;33(48):18906-16
pubmed: 24285896
Cognition. 2018 Jun;175:36-52
pubmed: 29459238
Nat Rev Neurosci. 2007 Dec;8(12):976-87
pubmed: 18026167
Cortex. 2016 Sep;82:147-163
pubmed: 27389800
Philos Trans R Soc Lond B Biol Sci. 2007 May 29;362(1481):801-11
pubmed: 17412680
Neuropsychologia. 2017 Jun;100:131-143
pubmed: 28450204
J Cogn Neurosci. 2013 Dec;25(12):2107-23
pubmed: 23806177
Nature. 1975 Feb 6;253(5491):437-8
pubmed: 1110787
Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12554-9
pubmed: 19617569
Cogn Neuropsychol. 2019 Oct - Dec;36(7-8):313-335
pubmed: 31451020
Brain Lang. 2016 Jun-Jul;157-158:81-94
pubmed: 27208858
Cereb Cortex. 2015 Nov;25(11):4319-33
pubmed: 25636912
Science. 1980 Jan 11;207(4427):203-5
pubmed: 7350657
J Cogn Neurosci. 2007 Sep;19(9):1542-55
pubmed: 17714015
Lang Cogn Neurosci. 2015 May 1;30(4):420-429
pubmed: 25914889
Neuroimage. 2005 Feb 1;24(3):624-34
pubmed: 15652298
Nat Rev Neurosci. 2017 Jan;18(1):42-55
pubmed: 27881854
J Neurophysiol. 2019 Apr 1;121(4):1513-1534
pubmed: 30785825
Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5072-81
pubmed: 27503892
Trends Cogn Sci. 2015 Jun;19(6):304-13
pubmed: 25980649
Top Cogn Sci. 2010 Jul;2(3):407-19
pubmed: 25163869
J Cogn Neurosci. 2006 Jun;18(6):1018-28
pubmed: 16839307
Trends Cogn Sci. 2011 Nov;15(11):527-36
pubmed: 22001867
Brain Cogn. 2011 Apr;75(3):299-309
pubmed: 21211892
Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11732-7
pubmed: 26305927
Brain. 2002 Jul;125(Pt 7):1583-93
pubmed: 12077007
Psychon Bull Rev. 2019 Dec;26(6):1850-1869
pubmed: 31290008
Cortex. 2019 Nov;120:308-325
pubmed: 31394366
Ann N Y Acad Sci. 2016 Apr;1369(1):132-53
pubmed: 27096882
J Vis. 2014 Jan 16;14(1):
pubmed: 24434626
Behav Brain Sci. 2002 Dec;25(6):657-74; discussion 674-725
pubmed: 14598623
Neuropsychologia. 2004;42(13):1788-804
pubmed: 15351628
J Exp Psychol Gen. 1986 Sep;115(3):281-94
pubmed: 2944988
Neurosci Lett. 2009 Aug 14;459(3):142-6
pubmed: 19427368
Nature. 1996 Sep 19;383(6597):254-6
pubmed: 8805700
Cereb Cortex. 2017 Sep 1;27(9):4379-4395
pubmed: 27522069
Nat Commun. 2020 Jun 12;11(1):3002
pubmed: 32532982
Annu Rev Psychol. 2011;62:621-47
pubmed: 20809790
Cereb Cortex. 2012 Jul;22(7):1593-603
pubmed: 21893681
Front Hum Neurosci. 2019 Oct 25;13:380
pubmed: 31708762
Neuropsychologia. 2015 Feb;68:176-89
pubmed: 25582406
Neuropsychologia. 2018 Apr;112:31-39
pubmed: 29476765
Neuroimage. 2015 Feb 1;106:72-85
pubmed: 25463475
Neuroimage. 2016 Oct 1;139:74-93
pubmed: 27261158
Cogn Psychol. 2001 Jun;42(4):317-67
pubmed: 11368527
Cortex. 2016 Sep;82:72-85
pubmed: 27367793
Cogn Neurosci. 2017 Jul;8(3):167-176
pubmed: 27386919
J Cogn Neurosci. 1997 Nov;9(6):714-26
pubmed: 23964594
Philos Trans R Soc Lond B Biol Sci. 2020 Jan 6;375(1789):20180391
pubmed: 31735144
Neuropsychologia. 1971 Mar;9(1):97-113
pubmed: 5146491
Semin Speech Lang. 2008 Feb;29(1):5-17
pubmed: 18348088
Cogn Psychol. 2013 Nov;67(3):73-97
pubmed: 23959023
Annu Rev Neurosci. 2002;25:151-88
pubmed: 12052907
Cereb Cortex. 2018 Dec 1;28(12):4305-4318
pubmed: 29186345
Curr Biol. 2000 Jun 15;10(12):723-6
pubmed: 10873809
Cortex. 2018 Oct;107:188-203
pubmed: 28947063
J Neurol Sci. 1965 May-Jun;2(3):288-92
pubmed: 4860800
Neuroimage. 2017 May 15;152:619-627
pubmed: 28323162
Annu Rev Psychol. 2008;59:617-45
pubmed: 17705682
Neurosci Biobehav Rev. 2015 Apr;51:296-312
pubmed: 25697904
Neuroimage. 2011 Feb 1;54(3):2418-25
pubmed: 20974270
J Neurophysiol. 2014 Sep 1;112(5):1105-18
pubmed: 24872535
Front Hum Neurosci. 2016 Mar 08;10:94
pubmed: 27014025
Neurology. 1999 Mar 23;52(5):1038-43
pubmed: 10102425
J Neurol Neurosurg Psychiatry. 1985 May;48(5):407-12
pubmed: 2582094
J Physiol Paris. 2008 Jan-May;102(1-3):59-70
pubmed: 18448316
Cogn Neuropsychol. 2017 Sep;34(6):377-393
pubmed: 29188746
Cogn Sci. 2017 Jan;41(1):70-101
pubmed: 26923431
Trends Cogn Sci. 2020 Apr;24(4):270-284
pubmed: 32160565
Nat Hum Behav. 2018 Mar;2(3):200-204
pubmed: 31620646
Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21219-21227
pubmed: 31570622
Neuropsychologia. 2015 Jan;67:63-81
pubmed: 25484306
J Cogn Neurosci. 2012 Aug;24(8):1766-78
pubmed: 22621260
Brain Res Cogn Brain Res. 2002 May;13(3):363-75
pubmed: 11919001
Brain. 2010 Nov;133(11):3256-68
pubmed: 20952377
J Neurosci. 2020 Jun 3;40(23):4536-4550
pubmed: 32317387
J Cogn Neurosci. 2008 Nov;20(11):2037-57
pubmed: 18416681
Cereb Cortex. 2016 Apr;26(4):1377-87
pubmed: 25316341
J Neurosci. 2013 Jun 19;33(25):10552-8
pubmed: 23785167
Mem Cognit. 2020 Oct;48(7):1181-1195
pubmed: 32430889
Psychol Sci. 2013 Sep;24(9):1816-23
pubmed: 23842954
Trends Cogn Sci. 2001 Jun 1;5(6):244-252
pubmed: 11390295
Trends Cogn Sci. 2004 Oct;8(10):472-8
pubmed: 15450512
J Neurosci. 2018 Nov 7;38(45):9689-9699
pubmed: 30249790
Nat Commun. 2018 Mar 6;9(1):963
pubmed: 29511192