Temporal Trends in the Use of Computed Tomographic Pulmonary Angiography for Suspected Pulmonary Embolism in the Emergency Department : A Retrospective Analysis.


Journal

Annals of internal medicine
ISSN: 1539-3704
Titre abrégé: Ann Intern Med
Pays: United States
ID NLM: 0372351

Informations de publication

Date de publication:
06 2023
Historique:
medline: 21 6 2023
pubmed: 22 5 2023
entrez: 22 5 2023
Statut: ppublish

Résumé

Recently, validated clinical decision rules have been developed that avoid unnecessary use of computed tomographic pulmonary angiography (CTPA) in patients with suspected pulmonary embolism (PE) in the emergency department (ED). To measure any resulting change in CTPA use for suspected PE. Retrospective analysis. 26 European EDs in 6 countries. Patients with CTPA performed for suspected PE in the ED during the first 7 days of each odd month between January 2015 and December 2019. The primary end points were the CTPAs done for suspected PE in the ED and the number of PEs diagnosed in the ED each year adjusted to an annual census of 100 000 ED visits. Temporal trends were estimated using generalized linear mixed regression models. 8970 CTPAs were included (median age, 63 years; 56% female). Statistically significant temporal trends for more frequent use of CTPA (836 per 100 000 ED visits in 2015 vs. 1112 in 2019; Data were limited to 7 days every 2 months. Despite the recent validation of clinical decision rules to limit the use of CTPA, an increase in the CTPA rate along with more diagnosed PEs and especially low-risk PEs were instead observed. None specific for this study.

Sections du résumé

BACKGROUND
Recently, validated clinical decision rules have been developed that avoid unnecessary use of computed tomographic pulmonary angiography (CTPA) in patients with suspected pulmonary embolism (PE) in the emergency department (ED).
OBJECTIVE
To measure any resulting change in CTPA use for suspected PE.
DESIGN
Retrospective analysis.
SETTING
26 European EDs in 6 countries.
PATIENTS
Patients with CTPA performed for suspected PE in the ED during the first 7 days of each odd month between January 2015 and December 2019.
MEASUREMENTS
The primary end points were the CTPAs done for suspected PE in the ED and the number of PEs diagnosed in the ED each year adjusted to an annual census of 100 000 ED visits. Temporal trends were estimated using generalized linear mixed regression models.
RESULTS
8970 CTPAs were included (median age, 63 years; 56% female). Statistically significant temporal trends for more frequent use of CTPA (836 per 100 000 ED visits in 2015 vs. 1112 in 2019;
LIMITATION
Data were limited to 7 days every 2 months.
CONCLUSION
Despite the recent validation of clinical decision rules to limit the use of CTPA, an increase in the CTPA rate along with more diagnosed PEs and especially low-risk PEs were instead observed.
PRIMARY FUNDING SOURCE
None specific for this study.

Identifiants

pubmed: 37216659
doi: 10.7326/M22-3116
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

761-768

Investigateurs

Mouna Berroukeche (M)
Anthony Chauvin (A)
Anne-Charlotte Dekeister (AC)
Mostafa El Hajjam (M)
Sami Ellouze (S)
Olivier Ganansia (O)
Julien Grosjean (J)
Quentin Le Bastard (Q)
Thomas Moumneh (T)
Milan Najdawi (M)
Laurent Pereira (L)
Isabelle Piazza (I)
Sarah Ponticello (S)
Jason Pott (J)
Clément Ricordeau (C)
Julie Robert (J)
Pascal Rousset (P)
Imogen Skene (I)
Clara Vignau (C)
Youri Yordanov (Y)

Auteurs

Melanie Roussel (M)

Sorbonne Université, UMR Inserm 1166, IHU ICAN, Paris; Emergency Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France (M.R., Y.F.).

Ben Bloom (B)

Emergency Department, Royal London Hospital, London, United Kingdom (B.B.).

Mehdi Taalba (M)

Emergency Department, Rouen University Hospital, Rouen, France (M.T.).

Christophe Choquet (C)

Emergency Department, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France (C. Choquet).

Delphine Douillet (D)

Department of Emergency Medicine, University Hospital of Angers, Angers; and UNIV Angers, UMR MitoVasc CNRS 6215 INSERM 1083, Angers, France (D.D.).

Florent Fémy (F)

Emergency Department, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, Université Paris Cite, Paris; and Toxicology and Chemical Risks Department, French Armed Forces Biomedical Institute, Brétigny-sur-Orge, France (F.F.).

Alexis Marouk (A)

Emergency Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France (A. Marouk).

Judith Gorlicki (J)

Emergency Department, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris, Bobigny, France (J. Golicki).

Camille Gerlier (C)

Emergency Department, Hôpital Saint-Joseph, Paris, France (C.G.).

Richard Macrez (R)

Emergency Department, CHU Caen Côte de Nacre, Normandie Université UNICAEN, INSERM PhIND Institut Blood and Brain, Caen, France (R.M.).

Emilien Arnaud (E)

Department of Emergency Medicine, Amiens-Picardy University Hospital, Amiens, France (E.A.).

Rudy Bompard (R)

Emergency Department, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, France (R.B.).

Emmanuel Montassier (E)

Emergency Department, CHU Nantes, Nantes, France (E.M.).

Olivier Hugli (O)

Emergency Department, Lausanne University Hospital Emergency Care Service, Lausanne, Switzerland (O.H.).

Charlotte Czopik (C)

Emergency Department, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France (C. Czopik).

Xavier Eyer (X)

Emergency Department, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France (X.E.).

Axel Benhamed (A)

Emergency Department, Hospices Civils de Lyon, Lyon, France (A.B., M.D.).

Olivier Peyrony (O)

Emergency Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France (O.P.).

Tahar Chouihed (T)

Emergency Department, University Hospital of Nancy, Nancy, France (T.C.).

Andrea Penaloza (A)

Emergency Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium (A.P.).

Alessio Marra (A)

Emergency Department, ASST Papa Giovanni XXIII, Bergamo, Italy (A. Marra).

Said Laribi (S)

Tours University, Emergency Medicine Department, Tours University Hospital, Tours, France (S.L.).

Paul-Georges Reuter (PG)

Emergency Department, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, Boulogne; and Université Versailles-Saint Quentin en Yvelines, Boulogne, France (P.-G.R.).

Wilhelm Behringer (W)

Department of Emergency Medicine, Medical University Vienna, Vienna General Hospital, Vienna, Austria (W.B.).

Marion Douplat (M)

Emergency Department, Hospices Civils de Lyon, Lyon, France (A.B., M.D.).

Jeremy Guenezan (J)

Emergency Department, University Hospital of Poitiers, Poitiers, France (J. Guenezen).

Nicolas Javaud (N)

Emergency Department, Hôpital Louis-Mourier, Assistance Publique-Hôpitaux de Paris, Colombes; and Reference Center for Bradykinin Angiodema (CReAk), Université Paris Cite, Colombes, France (N.J.).

Olivier Lucidarme (O)

Sorbonne Université, UMR Inserm 1166, IHU ICAN, Paris; and Sorbonne Université, CNRS, INSERM, Laboratoire d'Imagerie Biomédicale LIB, Paris, France (O.L.).

Marine Cachanado (M)

Department of Clinical Pharmacology and Clinical Research Platform Paris-East (URCEST-CRC-CRB), Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France (M.C., A.A.).

Ainhoa Aparicio-Monforte (A)

Department of Clinical Pharmacology and Clinical Research Platform Paris-East (URCEST-CRC-CRB), Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France (M.C., A.A.).

Yonathan Freund (Y)

Department of Clinical Pharmacology and Clinical Research Platform Paris-East (URCEST-CRC-CRB), Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France (M.C., A.A.).

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