A comprehensive review of healthy effects of vegetarian diets.


Journal

Nutrition, metabolism, and cardiovascular diseases : NMCD
ISSN: 1590-3729
Titre abrégé: Nutr Metab Cardiovasc Dis
Pays: Netherlands
ID NLM: 9111474

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 09 09 2022
revised: 04 04 2023
accepted: 05 04 2023
medline: 19 6 2023
pubmed: 23 5 2023
entrez: 22 5 2023
Statut: ppublish

Résumé

A comprehensive review comparing the effect of vegetarian (V) and non-vegetarian (NV) diets on the major cardiometabolic diseases' outcomes was performed. We performed literature research (up to December 31, 2022) of the evidence separately for vascular disease (VD), obesity (OB), dyslipidemia (Dysl), hypertension (HPT), type 2 diabetes (T2D), metabolic syndrome (MetS), analyzing only cohort studies and randomized controlled studies (RCTs) and comparing the effect of V and NV diets. Cohort studies showed advantages of V diets compared to NV diets on incidence and/or mortality risk for ischemic heart disease, overweight and OB risk. Most cohort studies showed V had lower risk of HPT and lower blood pressure (BP) than NV and V diets had positive effects on T2D risk or plasma parameters. The few cohort studies on the risk of MetS reported mixed results. In RCTs, V diets, mainly low-fat-vegan ones, led to greater weight loss and improved glycemic control than NV diets and in the only one RCT a partial regression of coronary atherosclerosis. In most RCTs, V diets significantly reduced LDL-C levels (but also decreased HDL-C levels) and BP. In this comprehensive review of the association between V diets and cardiometabolic outcomes, we found that following this type of diet may help to prevent most of these diseases. However, the non-uniformity of the studies, due to ethnic, cultural, and methodological differences, does not allow for generalizing the present results and drawing definitive conclusions. Further, well-designed studies are warranted to confirm the consistency of our conclusions.

Identifiants

pubmed: 37217433
pii: S0939-4753(23)00149-7
doi: 10.1016/j.numecd.2023.04.005
pii:
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1308-1315

Informations de copyright

Copyright © 2023 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

C Agnoli (C)

Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

L Baroni (L)

Scientific Society for Vegetarian Nutrition - SSNV, Venice (VE), Italy.

I Bertini (I)

Independent Researcher, Rome, Italy.

S Ciappellano (S)

Department of Food, Environmental and Nutritional Sciences (DeFENS), Division of Human Nutrition, University of Milan, Italy.

A Fabbri (A)

Department of Food and Drug Science, University of Parma, Italy.

S Goggi (S)

Nutrition and Dietetic Department, Plant Based Clinic, via Giannone 9, 20154, Milano, Italy.

D Metro (D)

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125, Messina, Italy.

M Papa (M)

Messina Provincial Health Authority, Messina, Italy.

R Sbarbati (R)

Independent researcher, Ancona, Italy.

M L Scarino (ML)

Research Institute for Food and Nutrition, Council for Agricultural Research and Economics, Rome, Italy.

N Pellegrini (N)

Department of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy. Electronic address: nicoletta.pellegrini@uniud.it.

S Sieri (S)

Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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Classifications MeSH