Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
22 05 2023
22 05 2023
Historique:
received:
03
11
2022
accepted:
10
05
2023
medline:
24
5
2023
pubmed:
23
5
2023
entrez:
22
5
2023
Statut:
epublish
Résumé
Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral diseases on record, affects over 22 species of reef-building coral and is decimating reefs throughout the Caribbean. To understand how different coral species and their algal symbionts (family Symbiodiniaceae) respond to this disease, we examine the gene expression profiles of colonies of five species of coral from a SCTLD transmission experiment. The included species vary in their purported susceptibilities to SCTLD, and we use this to inform gene expression analyses of both the coral animal and their Symbiodiniaceae. We identify orthologous coral genes exhibiting lineage-specific differences in expression that correlate to disease susceptibility, as well as genes that are differentially expressed in all coral species in response to SCTLD infection. We find that SCTLD infection induces increased expression of rab7, an established marker of in situ degradation of dysfunctional Symbiodiniaceae, in all coral species accompanied by genus-level shifts in Symbiodiniaceae photosystem and metabolism gene expression. Overall, our results indicate that SCTLD infection induces symbiophagy across coral species and that the severity of disease is influenced by Symbiodiniaceae identity.
Identifiants
pubmed: 37217477
doi: 10.1038/s41467-023-38612-4
pii: 10.1038/s41467-023-38612-4
pmc: PMC10202950
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
2915Informations de copyright
© 2023. The Author(s).
Références
Trends Microbiol. 2017 Feb;25(2):125-140
pubmed: 27919551
Nucleic Acids Res. 2016 Jan 4;44(D1):D7-19
pubmed: 26615191
Bioinformatics. 2018 Sep 1;34(17):i884-i890
pubmed: 30423086
PeerJ. 2020 Jun 9;8:e9289
pubmed: 32551200
PLoS One. 2012;7(4):e35269
pubmed: 22529998
Environ Microbiol. 2022 Mar;24(3):1166-1182
pubmed: 34431191
ISME Commun. 2023 Apr 3;3(1):27
pubmed: 37009785
Trends Biochem Sci. 2008 Dec;33(12):592-600
pubmed: 18926707
Infect Immun. 2005 Dec;73(12):7827-35
pubmed: 16299272
Glob Chang Biol. 2020 Feb 12;:
pubmed: 32048447
Mol Ecol. 2022 May;31(9):2594-2610
pubmed: 35229964
J Exp Biol. 2008 Oct;211(Pt 19):3059-66
pubmed: 18805804
Ecol Evol. 2019 Dec 12;10(1):451-466
pubmed: 31993121
Trends Microbiol. 2021 Apr;29(4):320-333
pubmed: 33041180
Nat Biotechnol. 2011 May 15;29(7):644-52
pubmed: 21572440
Genome Biol. 2014;15(12):550
pubmed: 25516281
Sci Rep. 2016 Aug 22;6:31508
pubmed: 27545322
Nat Rev Immunol. 2011 Jun 10;11(7):457-68
pubmed: 21660053
PLoS One. 2020 Nov 11;15(11):e0241871
pubmed: 33175886
Dis Aquat Organ. 2009 Nov 16;87(1-2):117-33
pubmed: 20095247
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1387-92
pubmed: 23297204
Sci Rep. 2017 Jun 1;7(1):2609
pubmed: 28572677
Mol Ecol. 2019 Dec;28(24):5265-5281
pubmed: 31693775
NPJ Biofilms Microbiomes. 2018 Jul 4;4:14
pubmed: 30002868
Mol Ecol. 2012 May;21(10):2440-54
pubmed: 22490231
Biochem Biophys Res Commun. 2003 Aug 29;308(3):586-95
pubmed: 12914791
J Exp Biol. 2010 Mar 15;213(6):934-45
pubmed: 20190118
Bioinformatics. 2015 Oct 1;31(19):3210-2
pubmed: 26059717
Retrovirology. 2015 Aug 14;12:72
pubmed: 26268989
Cancer Res. 2008 Dec 1;68(23):9686-92
pubmed: 19047146
BMC Genomics. 2015 May 09;16:371
pubmed: 25956907
Front Microbiol. 2020 Apr 23;11:681
pubmed: 32425901
F1000Res. 2015 Dec 30;4:1521
pubmed: 26925227
Sci Rep. 2021 Apr 21;11(1):8566
pubmed: 33883581
Cell. 2021 May 27;184(11):2973-2987.e18
pubmed: 33945788
Front Microbiol. 2016 Jun 21;7:991
pubmed: 27446031
PeerJ. 2018 May 23;6:e4816
pubmed: 29844969
Front Microbiol. 2019 Sep 24;10:2244
pubmed: 31608047
EMBO J. 2007 Mar 21;26(6):1532-41
pubmed: 17318178
Curr Biol. 2016 Dec 5;26(23):3190-3194
pubmed: 27866895
EMBO Rep. 2013 Feb;14(2):164-71
pubmed: 23208550
Autophagy. 2009 Feb;5(2):211-6
pubmed: 19066451
Bioinformatics. 2010 Mar 1;26(5):680-2
pubmed: 20053844
Semin Immunol. 2014 Aug;26(4):277-94
pubmed: 25086685
Front Microbiol. 2020 Oct 26;11:569354
pubmed: 33193161
Science. 2010 Jun 18;328(5985):1523-8
pubmed: 20558709
Nat Commun. 2023 May 22;14(1):2915
pubmed: 37217477
Mol Ecol. 2021 Jul;30(14):3468-3484
pubmed: 33894013
Nucleic Acids Res. 2021 Jan 8;49(D1):D480-D489
pubmed: 33237286
Nat Protoc. 2013 Aug;8(8):1494-512
pubmed: 23845962
Biotechniques. 2007 Jul;43(1 Suppl):25-30
pubmed: 17936939
Bioinformatics. 2015 Sep 1;31(17):2912-4
pubmed: 25964631
Nat Methods. 2017 Apr;14(4):417-419
pubmed: 28263959
Front Mar Sci. 2021 Sep 22;8:1-8
pubmed: 35685121
Mol Ecol. 2018 Dec;27(24):5180-5194
pubmed: 30411823
Syst Biol. 2015 Sep;64(5):695-708
pubmed: 26169525
Mol Ecol Resour. 2019 Jul;19(4):1063-1080
pubmed: 30740899
J Biol Chem. 2008 Oct 31;283(44):29822-30
pubmed: 18723511
Curr Opin Microbiol. 2002 Dec;5(6):602-7
pubmed: 12457705
Microbiol Resour Announc. 2022 Feb 17;11(2):e0119921
pubmed: 35175123
Mol Ecol. 2018 Feb;27(4):1065-1080
pubmed: 29334418
Genome Biol. 2015 Aug 06;16:157
pubmed: 26243257
Genome Biol Evol. 2016 Feb 11;8(3):665-80
pubmed: 26868597
Cell Stress Chaperones. 2011 Jan;16(1):69-80
pubmed: 20821176