Mesotheliomas in Children.


Journal

Advances in anatomic pathology
ISSN: 1533-4031
Titre abrégé: Adv Anat Pathol
Pays: United States
ID NLM: 9435676

Informations de publication

Date de publication:
01 Jul 2023
Historique:
medline: 9 6 2023
pubmed: 23 5 2023
entrez: 22 5 2023
Statut: ppublish

Résumé

Mesotheliomas are rare and aggressive tumors that originate from mesothelial cells. Although exceedingly rare, these tumors may occur in children. Different from adult mesotheliomas, however, environmental exposures particularly to asbestos do not appear to play a major role in mesotheliomas in children, in whom specific genetic rearrangements driving these tumors have been identified in recent years. These molecular alterations may increasingly offer opportunities for targeted therapies in the future, which may provide better outcomes for these highly aggressive malignant neoplasms.

Identifiants

pubmed: 37217834
doi: 10.1097/PAP.0000000000000403
pii: 00125480-202307000-00006
doi:

Substances chimiques

Asbestos 1332-21-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-279

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors have no funding or conflicts of interest to disclose.

Références

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Auteurs

Eduardo Zambrano (E)

Department of Pathology, University of Pittsburgh Medical Center (UPMC) Children's Hospital of Pittsburgh, Pittsburgh, PA.

Andrés Matoso (A)

Departments of Pathology.
Urology.
Oncology, Johns Hopkins School of Medicine, Baltimore, MD.

Miguel Reyes-Múgica (M)

Department of Pathology, University of Pittsburgh Medical Center (UPMC) Children's Hospital of Pittsburgh, Pittsburgh, PA.

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