The association of perceived discrimination with dementia risk in Black older adults.
dementia risk
discrimination
macro level factors
older Black adults
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
14
04
2023
received:
13
02
2023
accepted:
18
04
2023
medline:
23
10
2023
pubmed:
23
5
2023
entrez:
23
5
2023
Statut:
ppublish
Résumé
Non-Hispanic Black, compared to non-Hispanic White, older adults are at increased risk for dementia. This may be due partly to greater exposure to psychosocial stressors, such as discrimination; however, few studies have examined this association. We examined the association of perceived discrimination (e.g., everyday, lifetime, and discrimination burden) with dementia risk in 1583 Black adults co-enrolled in the Atherosclerosis Risk in Communities (ARIC) Study and the Jackson Heart Study (JHS). Perceived discrimination (defined continuously and using tertiles) was assessed at JHS Exam 1 (2000-2004; mean age ± SD:66.2 ± 5.5) and related to dementia risk through ARIC visit 6 (2017) using covariate-adjusted Cox proportional hazards models. Associations of perceived everyday, lifetime, and burden of discrimination with dementia risk were not supported in age-adjusted models or demographic- and cardiovascular health-adjusted models. Results were similar across sex, income, and education. In this sample, associations between perceived discrimination and dementia risk were not supported. In Black older adults perceived discrimination not associated with dementia risk. Younger age and greater education linked to greater perceived discrimination. Older age and less education among factors associated with dementia risk. Factors increasing exposure to discrimination (education) are also neuroprotective.
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
4346-4356Subventions
Organisme : NHLBI NIH HHS
ID : U01 HL096917
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096899
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096812
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096814
Pays : United States
Organisme : HHS
ID : 75N92022D00001
Pays : United States
Organisme : HHS
ID : 75N92022D00002
Pays : United States
Organisme : HHS
ID : 75N92022D00003
Pays : United States
Organisme : HHS
ID : 75N92022D00004
Pays : United States
Organisme : HHS
ID : 75N92022D00005
Pays : United States
Organisme : HHS
ID : U01HL096812
Pays : United States
Organisme : HHS
ID : U01HL096814
Pays : United States
Organisme : HHS
ID : U01HL096899
Pays : United States
Organisme : HHS
ID : U01HL096902
Pays : United States
Organisme : HHS
ID : U01HL096917
Pays : United States
Organisme : NIH HHS
ID : 3K01AG054693
Pays : United States
Organisme : NIMHD NIH HHS
ID : HHSN268201800013I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201800014I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201800015I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201800010I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201800011I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201800012I
Pays : United States
Informations de copyright
© 2023 Alzheimer's Association. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.
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