Use or Misuse of Albumin in Critical Ill Patients.

cirrhosis hemodynamic immunology sepsis volume treatment

Journal

Diseases (Basel, Switzerland)
ISSN: 2079-9721
Titre abrégé: Diseases
Pays: Switzerland
ID NLM: 101636232

Informations de publication

Date de publication:
28 04 2023
Historique:
received: 04 04 2023
revised: 26 04 2023
accepted: 26 04 2023
medline: 23 5 2023
pubmed: 23 5 2023
entrez: 23 5 2023
Statut: epublish

Résumé

Since 1940 albumin has been used worldwide and is widely available commercially since this time. However, a meta-analysis in 1998 challenged the use of albumin and identified a trend toward higher mortality in critically ill patients who had received albumin. Since then, many studies including multicenter randomized controlled trials have been carried out investigating the safety and efficacy of albumin treatment in different patient cohorts. In this context, patient cohorts that benefit from albumin were identified. However, particularly in non-liver patients, the use of albumin remains controversial. In our comprehensive review, we would like to highlight the most important studies in the recent 20 years and therefore offer an evidence-based outlook for the use of albumin for patients treated in the ICU.

Identifiants

pubmed: 37218881
pii: diseases11020068
doi: 10.3390/diseases11020068
pmc: PMC10204385
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Fuat Hakan Saner (FH)

Adult Transplant ICU, Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia.

Bjoern-Ole Stueben (BO)

Department of General-, Visceral-, and Transplant Surgery, Medical Center University Duisburg-Essen, 45147 Essen, Germany.

Dieter Peter Hoyer (DP)

Department of General-, Visceral-, and Transplant Surgery, Medical Center University Duisburg-Essen, 45147 Essen, Germany.

Dieter Clemens Broering (DC)

Adult Transplant ICU, Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia.

Dmitri Bezinover (D)

Department of Anesthesiology and Critical Care 3400 Spruce Street, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

Classifications MeSH