Patient perspectives of antiretroviral pharmacy services: A cross-sectional cohort study.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 30 01 2023
accepted: 28 03 2023
medline: 25 5 2023
pubmed: 23 5 2023
entrez: 23 5 2023
Statut: epublish

Résumé

Adherence to antiretroviral therapy (ART) remains the main predictor of sustained HIV virologic suppression for people with HIV (PWH). Mail-order pharmacy services are often offered to patients as an alternative option to traditional pharmacy services. Some payers mandate ART to be dispensed from specific mail-order pharmacies regardless of patient choice complicating ART adherence for patients affected by social disparities. Yet, little is known about patient perspectives regarding mail-order mandates. Eligible patients of the HIV program at University of Nebraska Medical Center with experience receiving ART from both a local and mail-order pharmacy were invited to complete a 20-question survey with three core sections: experiences/perspectives on local and mail-order pharmacy settings; pharmacy attributes rankings; and pharmacy preference. Paired t-tests and Mann-Whitney tests were used to compare the agreement scores of pharmacy attributes. Sixty patients (N = 146; 41.1%) responded to the survey. Mean age was 52 years. Most were male (93%) and White (83%). The majority of participants were on ART for HIV treatment (90%) and 60% were using mail-order pharmacies for their prescription services. Significant scoring differences (p<0.05) were observed for all pharmacy attributes favoring local pharmacies. Refilling ease was the most important attribute noted. More respondents (68%) preferred local pharmacies versus mail-order pharmacies. Payer associated mail-order pharmacy mandates were experienced by 78% with half believing the mandates impacted their medical care negatively. In this cohort study, respondents preferred local pharmacies compared to mail-order pharmacy for ART prescription services and noted ease of refilling as the most important pharmacy attribute. Two-thirds of respondents believed mail-order pharmacy mandates negatively affected their health. Insurance payers should consider the removal of mail-order pharmacy mandates to allow patient choice of pharmacy, which may help remove barriers to ART adherence and improve long-term health outcomes.

Sections du résumé

BACKGROUND
Adherence to antiretroviral therapy (ART) remains the main predictor of sustained HIV virologic suppression for people with HIV (PWH). Mail-order pharmacy services are often offered to patients as an alternative option to traditional pharmacy services. Some payers mandate ART to be dispensed from specific mail-order pharmacies regardless of patient choice complicating ART adherence for patients affected by social disparities. Yet, little is known about patient perspectives regarding mail-order mandates.
METHODS
Eligible patients of the HIV program at University of Nebraska Medical Center with experience receiving ART from both a local and mail-order pharmacy were invited to complete a 20-question survey with three core sections: experiences/perspectives on local and mail-order pharmacy settings; pharmacy attributes rankings; and pharmacy preference. Paired t-tests and Mann-Whitney tests were used to compare the agreement scores of pharmacy attributes.
RESULTS
Sixty patients (N = 146; 41.1%) responded to the survey. Mean age was 52 years. Most were male (93%) and White (83%). The majority of participants were on ART for HIV treatment (90%) and 60% were using mail-order pharmacies for their prescription services. Significant scoring differences (p<0.05) were observed for all pharmacy attributes favoring local pharmacies. Refilling ease was the most important attribute noted. More respondents (68%) preferred local pharmacies versus mail-order pharmacies. Payer associated mail-order pharmacy mandates were experienced by 78% with half believing the mandates impacted their medical care negatively.
CONCLUSIONS
In this cohort study, respondents preferred local pharmacies compared to mail-order pharmacy for ART prescription services and noted ease of refilling as the most important pharmacy attribute. Two-thirds of respondents believed mail-order pharmacy mandates negatively affected their health. Insurance payers should consider the removal of mail-order pharmacy mandates to allow patient choice of pharmacy, which may help remove barriers to ART adherence and improve long-term health outcomes.

Identifiants

pubmed: 37220118
doi: 10.1371/journal.pone.0285694
pii: PONE-D-23-02690
pmc: PMC10204950
doi:

Substances chimiques

Anti-Retroviral Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0285694

Informations de copyright

Copyright: © 2023 Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

J Am Pharm Assoc (2003). 2012 Sep-Oct;52(5):e67-73
pubmed: 23023860
PLoS Med. 2016 Nov 29;13(11):e1002183
pubmed: 27898679
Lancet. 2021 Mar 20;397(10279):1127-1138
pubmed: 33617778
J Manag Care Spec Pharm. 2018 Apr;24(4):317-326
pubmed: 29578855
Lancet. 2016 Jan 2;387(10013):53-60
pubmed: 26364263
Open Forum Infect Dis. 2019 Mar 27;6(5):ofz148
pubmed: 31139668
Lancet Infect Dis. 2014 Sep;14(9):820-9
pubmed: 25065857
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Int J Behav Med. 2023 Jun;30(3):345-355
pubmed: 35499813
N Engl J Med. 2015 Aug 27;373(9):795-807
pubmed: 26192873
AIDS Behav. 2021 Jul;25(7):2301-2315
pubmed: 33515132
Soc Sci Med. 2000 Jun;50(11):1599-605
pubmed: 10795966
Am Psychol. 2013 May-Jun;68(4):197-209
pubmed: 23688088
Am J Manag Care. 2010 Jan;16(1):33-40
pubmed: 20148603
JAMA. 2019 Mar 5;321(9):844-845
pubmed: 30730529
AIDS Care. 2020 Nov;32(11):1372-1378
pubmed: 32362129
Biotechnol Healthc. 2008 Jul;5(2):50-1
pubmed: 22478714
Int J STD AIDS. 2012 May;23(5):351-5
pubmed: 22648890
Int J STD AIDS. 2015 Feb;26(2):93-7
pubmed: 24733153
Res Social Adm Pharm. 2018 Feb;14(2):153-161
pubmed: 28291673
AIDS Care. 2021 May;33(5):566-574
pubmed: 32342701
Lancet. 2021 Mar 20;397(10279):1151-1156
pubmed: 33617770
J Biomed Inform. 2019 Jul;95:103208
pubmed: 31078660
J Manag Care Pharm. 2009 Jan-Feb;15(1):32-41
pubmed: 19125548
Am J Manag Care. 2013 Nov;19(11):882-7
pubmed: 24511986
Patient Prefer Adherence. 2012;6:323-9
pubmed: 22563240
Clin Infect Dis. 2007 Oct 1;45(7):908-15
pubmed: 17806060
AIDS Patient Care STDS. 2014 Nov;28(11):579-86
pubmed: 25290556
AIDS Behav. 2022 Nov;26(11):3480-3493
pubmed: 35445996

Auteurs

Yadi Liu (Y)

University of Nebraska Medical Center, College of Pharmacy, Omaha, NE, United States of America.

Elizabeth Lyden (E)

University of Nebraska Medical Center, College of Public Health, Omaha, NE, United States of America.

Renae Furl (R)

University of Nebraska Medical Center, College of Medicine, Omaha, NE, United States of America.

Joshua P Havens (JP)

University of Nebraska Medical Center, College of Pharmacy, Omaha, NE, United States of America.
University of Nebraska Medical Center, College of Medicine, Omaha, NE, United States of America.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH