Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case.
acute eosinophilic pneumonia
angiosarcoma
bronchoalveolar lavage
eosinophilic lung disease
eosinophilic pneumonia
paraneoplastic disorder
Journal
Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
10
04
2023
revised:
24
04
2023
accepted:
01
05
2023
medline:
23
5
2023
pubmed:
23
5
2023
entrez:
23
5
2023
Statut:
epublish
Résumé
This case report emphasizes that we should analyze a patient's signs and symptoms as a whole rather than relying exclusively on a common pattern to diagnose the condition and indicates that thorough histological investigation and sample collection are needed to accurately diagnose this malignancy. Angiosarcoma is a rare, fatal, and poorly understood malignant tumor of vascular endothelial cells which is a challenging disease to diagnose in the clinical settings and requires early diagnosis to achieve a favorable prognosis. Paraneoplastic syndromes associated with angiosarcoma can include hypercoagulability, thrombocytopenia, anemia, fever, weight loss, and night sweats. In some cases, the paraneoplastic syndrome can be the first sign of the underlying malignancy. Here, we present a 47-year-old individual with angiosarcoma over the right scapula accompanied by hemoptysis and other pulmonary complaints whom at first was thought to be metastatic polmunary involvement. However, the patient's dramatic response to corticosteroids, in addition to further imaging and paraclinical studies, led us to an acute eosinophilic pneumonia (AEP) diagnosis which is an eosinophilic infiltrations of alveolar spaces. The patient received chemotherapy for angiosarcoma and radiation, since the brachial nerve network was disrupted, leaving the tumor unresectable. After 3 years of continuous follow-up, the patient is now completely cured.
Identifiants
pubmed: 37220510
doi: 10.1002/ccr3.7348
pii: CCR37348
pmc: PMC10199819
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e7348Informations de copyright
© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
None.
Références
Respirol Case Rep. 2022 Aug 27;10(10):e01027
pubmed: 36051364
Am J Respir Crit Care Med. 1997 Jan;155(1):296-302
pubmed: 9001328
Clin Chest Med. 2016 Sep;37(3):535-56
pubmed: 27514599
Eur J Radiol. 2008 Mar;65(3):462-7
pubmed: 17537607
Lancet Oncol. 2010 Oct;11(10):983-91
pubmed: 20537949
Am J Cancer Res. 2019 Nov 01;9(11):2303-2313
pubmed: 31815036
Br J Radiol. 2017 Jul;90(1075):20170039
pubmed: 28471264
Arch Bronconeumol. 2004 Apr;40(4):188-90
pubmed: 15030735
Am J Respir Crit Care Med. 2018 Mar 15;197(6):728-736
pubmed: 29206477
Int J Oral Maxillofac Surg. 2014 Aug;43(8):917-23
pubmed: 24656496
Clin Nucl Med. 2014 May;39(5):450-2
pubmed: 23657141
Am J Surg Pathol. 2021 Jan;45(1):e1-e23
pubmed: 32796172
Nihon Kokyuki Gakkai Zasshi. 2007 Mar;45(3):223-32
pubmed: 17419433
Respirology. 2014 Oct;19(7):1059-65
pubmed: 24985714
Eur Respir J. 2013 Feb;41(2):402-9
pubmed: 22599359