Retrospective analysis of the appendiceal neoplasms: sampling technique may influence neoplasm detection.

colorectal surgery gastrointestinal tumours pathology

Journal

Postgraduate medical journal
ISSN: 1469-0756
Titre abrégé: Postgrad Med J
Pays: England
ID NLM: 0234135

Informations de publication

Date de publication:
19 May 2023
Historique:
received: 30 09 2021
accepted: 23 11 2021
medline: 25 5 2023
pubmed: 24 5 2023
entrez: 24 5 2023
Statut: ppublish

Résumé

Appendiceal neoplasms are uncommon entities that are usually determined incidentally during the histopathological examination. Different techniques used for the macroscopic sampling of appendectomy material may affect the determinating neoplasms. H&E-stained slides of 1280 cases who underwent appendectomy between 2013 and 2018 were reviewed retrospectively for histopathological features. Neoplasms were determined in 28 cases (3.09%); 1 lesion was observed in the proximal part of the appendix, 1 covering the entire length from proximal to distal and 26 in the distal part. In the 26 cases that observed in the distal part, the lesion was seen on both sides of the longitudinal section of the distal appendix in 20 cases, while it was seen on only one distal longitudinal section in the remaining 6 cases. The vast majority of appendiceal neoplasms are seen in the distal part of the appendix, and, in some cases, neoplasms might be seen on only one side of the distal section. Sampling only one-half of the distal part of the appendix, where tumours are most often observed, could result in some neoplasms being missed. Therefore, sampling the whole distal part would be more beneficial to determine small diameter tumours that do not create macroscopic findings.

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
Appendiceal neoplasms are uncommon entities that are usually determined incidentally during the histopathological examination. Different techniques used for the macroscopic sampling of appendectomy material may affect the determinating neoplasms.
MATERIALS AND METHODS METHODS
H&E-stained slides of 1280 cases who underwent appendectomy between 2013 and 2018 were reviewed retrospectively for histopathological features.
RESULTS RESULTS
Neoplasms were determined in 28 cases (3.09%); 1 lesion was observed in the proximal part of the appendix, 1 covering the entire length from proximal to distal and 26 in the distal part. In the 26 cases that observed in the distal part, the lesion was seen on both sides of the longitudinal section of the distal appendix in 20 cases, while it was seen on only one distal longitudinal section in the remaining 6 cases.
CONCLUSION CONCLUSIONS
The vast majority of appendiceal neoplasms are seen in the distal part of the appendix, and, in some cases, neoplasms might be seen on only one side of the distal section. Sampling only one-half of the distal part of the appendix, where tumours are most often observed, could result in some neoplasms being missed. Therefore, sampling the whole distal part would be more beneficial to determine small diameter tumours that do not create macroscopic findings.

Identifiants

pubmed: 37222057
pii: 7177364
doi: 10.1136/postgradmedj-2021-141244
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

183-188

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of Postgraduate Medical Journal. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Gizem Issin (G)

Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey.

Fatih Demir (F)

Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey.

Hasan Aktug Simsek (HA)

Department of Pathology, Eskisehir City Hospital, Eskisehir, Turkey.

Diren Vuslat Cagatay (DV)

Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey.

Mahir Tayfur (M)

Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey.

Mecdi Gurhan Balci (MG)

Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey.

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Classifications MeSH