Comparative Study on Phenolic Profile and Biological Activities of the Aerial Parts of Sinapis pubescens L. subsp. pubescens (Brassicaceae) Wild from Sicily (Italy).


Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 01 03 2023
accepted: 23 05 2023
medline: 26 6 2023
pubmed: 24 5 2023
entrez: 24 5 2023
Statut: ppublish

Résumé

This work aimed to investigate Sinapis pubescens subsp. pubescens spontaneously grown in Sicily (Italy) as new potential source of active metabolites; specifically, a comparative study on leaf, flower, and stem hydroalcoholic extracts was performed. Polyphenols were quantitatively determined by spectrophotometric methods and characterized by HPLC-PDA/ESI-MS; a total of 55 polyphenolic compounds were identified, highlighting considerably different qualitative-quantitative profiles. The extracts showed antioxidant activity, evaluated by in vitro assays; particularly, the leaf extract displayed the best radical scavenging activity (DPPH test) and reducing power, while the flower extract showed the greatest chelating activity. The antimicrobial properties of the extracts were investigated against bacteria and yeasts by standard methods; no antimicrobial activity was found against the strains tested. The extracts resulted to be non-toxic after preliminary toxicity evaluation by the Artemia salina lethality bioassay. The aerial parts of S. pubescens subsp. pubescens proved to be valuable sources of antioxidants for pharmaceutical and nutraceutical applications.

Identifiants

pubmed: 37222439
doi: 10.1002/cbdv.202300309
doi:

Substances chimiques

Plant Extracts 0
Phenols 0
Antioxidants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202300309

Subventions

Organisme : "Prof. Antonio Imbesi" Foundation
Organisme : Shimadzu and Merck Life Science Corporations

Informations de copyright

© 2023 The Authors. Chemistry & Biodiversity published by Wiley-VHCA AG, Zurich, Switzerland.

Références

F. M. Raimondo, G. Domina, V. Spadaro, Quad. Bot. Amb. Appl. 2010, 21, 189-252.
S. Pasta, A. La Rosa, G. Garfì, C. Marcenò, A. S. Gristina, F. Carimi, R. Guarino, Front. Plant Sci. 2020, 11, 388.
K. Kubitzki, C. Bayer, ‘Flowering plants. Dicotyledons - Malvales, Capparales and non-betalain Caryophyllales’, Springer, Berlin Heidelberg, 2003, p. 159.
A. Mikić, Genet. Res. 2016, 63, 1-6.
T. G. Tutin, V. H. Heywood, N. A. Burges, D. M. Moore, D. H. Valentine, S. M. Walters, D. A. Webb, ‘Flora Europea’, Cambridge University Press, Cambridge,1964, Vol. 1, p. 339.
https://brassibase.cos.uni-heidelberg.de/; Accessed January 27, 2023.
S. Pignatti, Flora d'Italia, Edagricole, Bologna, 2° Ed. 2017, Vol. 2, pp. 1028-1029.
F. Bartolucci, L. Peruzzi, G. Galasso, A. Albano, A. Alessandrini, N. M. G. Ardenghi, G. Astuti, G. Bacchetta, S. Ballelli, E. Banfi, G. Barberis, L. Bernardo, D. Bouvet, M. Bovio, L. Cecchi, R. Di Pietro, G. Domina, S. Fascetti, G. Fenu, F. Festi, B. Foggi, L. Gallo, G. Gottschlich, L. Gubellini, D. Iamonico, M. Iberite, P. Jiménez-Mejías, E. Lattanzi, D. Marchetti, E. Martinetto, R. R. Masin, P. Medagli, N. G. Passalacqua, S. Peccenini, R. Pennesi, B. Pierini, L. Poldini, F. Prosser, F. M. Raimondo, F. Roma-Marzio, L. Rosati, A. Santangelo, A. Scoppola, S. Scortegagna, A. Selvaggi, F. Selvi, A. Soldano, A. Stinca, R. P. Wagensommer, T. Wilhalm, F. Conti, Plant Biosyst. 2018, 152, 179-303.
M. L. Leporatti, S. Ivancheva, J. Ethnopharmacol. 2003, 87, 123-142.
A. Alachkar, A. Jaddouh, M. S. Elsheikh, A. R. Bilia, F. F. Vincieri, Nat. Prod. Commun. 2011, 6, 79-84.
R. Polat, F. Satıl, J. Ethnopharmacol. 2012, 139, 626-641.
T. Tuttolomondo, M. Licata, C. Leto, G. Bonsangue, M. L. Gargano, G. Venturella, S. La Bella, J. Ethnopharmacol. 2014, 157, 21-37.
Y. F. Xian, Z. Hu, S. P. Ip, J. N. Chen, Z. R. Su, X. P. Lai, Z. X. Lin, Phytomedicine 2018, 50, 196-204.
J. Lietzow, Food 2021, 10, 2089.
F. E. Amrati, M. Bourhia, M. Slighoua, A. Mohammad Salamatullah, A. Alzahrani, R. Ullah, A. Bari, D. Bousta, Saudi Pharm. J. 2021, 29, 1185-1204.
F. Lentini, F. Venza, J. Ethnobiol. Ethnomed. 2007, 3, 15.
D. Romano, A. Tribulato, S. Toscano, D. Scuderi, Acta Hortic. 2013, 1005, 197-204.
R. Di Novella, N. Di Novella, L. De Martino, E. Mancini, V. De Feo, J. Ethnopharmacol. 2013, 145, 328-342.
N. Biscotti, A. Pieroni, Acta Soc. Bot. Pol. 2015, 84, 327-338.
G. Mattalia, P. Corvo, A. Pieroni, Ethnobot. Res. Appl. 2020, 19, 38.
R. Jayabalan, P. Subathradevi, S. Marimuthu, M. Sathishkumar, K. Swaminathan, Food Chem. 2008, 109, 227-234.
M. Soto-Hernandez, M. Palma-Tenango, M. Garcia-Mateos, IntechOpen, London, 2017.
Y. Oulad El Majdoub, F. Alibrando, F. Cacciola, K. Arena, E. Pagnotta, R. Matteo, G. Micalizzi, L. Dugo, P. Dugo, L. Mondello, Molecules 2020, 25, 5421.
Y.-Q. Wang, L.-P. Hu, G.-M. Liu, D.-S. Zhang, H.-J. He, Molecules 2017, 22, 1262.
M. F. Taviano, E. Cavò, V. Spadaro, F. M. Raimondo, V. Musolino, F. Cacciola, Y. O. El Majdoub, L. Mondello, C. Condurso, F. Cincotta, A. Verzera, N. Miceli, Molecules 2021, 26, 4114.
E. Cavò, M. F. Taviano, F. Davì, F. Cacciola, Y. Oulad El Majdoub, L. Mondello, M. Ragusa, C. Condurso, M. Merlino, A. Verzera, N. Miceli, Molecules 2022, 27, 2768.
A. Martínez-Sánchez, R. Llorach, M. I. Gil, F. Ferreres, J. Agric. Food Chem. 2007, 55, 1356-1363.
A. Martínez-Sánchez, A. Gil-Izquierdo, M. I. Gil, F. Ferreres, J. Agric. Food Chem. 2008, 56, 2330-2340.
N. Miceli, A. Filocamo, S. Ragusa, F. Cacciola, P. Dugo, L. Mondello, M. Celano, V. Maggisano, M. F. Taviano, Chem. Biodiversity 2017, 14, e1700073.
J. Sun, Z. Xiao, L. Lin, G. E. Lester, Q. Wang, J. M. Harnly, P. Chen, J. Agric. Food Chem. 2013, 61, 10960-10970.
S. Schmidt, M. Zietz, M. Schreiner, S. Rohn, L. W. Kroh, A. Krumbein, Rapid Commun. Mass Spectrom. 2010, 24, 2009-2022.
N. Miceli, E. Cavò, M. Ragusa, F. Cacciola, L. Mondello, L. Dugo, R. Acquaviva, G. A. Malfa, A. Marino, M. D'Arrigo, M. F. Taviano, Molecules 2020, 25, 1461.
M. Rudrapal, S. J. Khairnar, J. Khan, A. B. Dukhyil, M. A. Ansari, M. N. Alomary, R. Devi, Front. Pharmacol. 2022, 13, 283.
S. Bounatirou, S. Smiti, M. G. Miguel, L. Faleiro, M. N. Rejeb, M. Neffati, M. M. Costa, A. C. Figueiredo, J. G. Barroso, L. G. Pedro, Food Chem. 2007, 105, 146-155.
J. Dai, R. J. Mumper, Molecules 2010, 15, 7313-7352.
I. D. Nwachukwu, R. A. Sarteshnizi, C. C. Udenigwe, R. E. Aluko, Molecules 2021, 26, 4865.
R. Tabaraki, F. Ghadiri, Int. Food Res. J. 2013, 20, 2111-2115.
B. Başyiğit, H. Alaşalvar, N. Doğan, C. Doğan, S. Berktaş, M. Çam, J. Food Meas. Charact. 2020, 14, 1671-1681.
N. E. Ntungwe, E. M. Domínguez-Martín, A. Roberto, J. Tavares, V. M. S. Isca, P. Pereira, M.-J. Cebola, P. Rijo, Curr. Pharm. Des. 2020, 26, 2892-2908.
M. R. Hamidi, B. Jovanova, T. K. Panovska, Maced. Pharm. Bull. 2014, 60, 9-18.
X. Gao, M. Ohlander, N. Jeppsson, L. Björk, V. Trajkovski, J. Agric. Food Chem. 2000, 48, 1485-1490.
M.-Y. Chang, C.-M. Liu, D.-E. Shieh, C.-Y. Chen, Biomed. Res. 2017, 28, 6431-6434.
R. Julkunen-Titto, J. Agric. Food Chem. 1985, 33, 213-217.
K. Arena, E. Trovato, F. Cacciola, L. Spagnuolo, E. Pannucci, P. Guarnaccia, L. Santi, P. Dugo, L. Mondello, L. Dugo, Molecules 2022, 27, 1727.
T. Lechhab, F. Salmoun, W. Lechhab, Y. Oulad El Majdoub, M. Russo, M. R. Testa Camillo, E. Trovato, P. Dugo, L. Mondello, F. Cacciola, Eur. Food Res. Technol. 2022, 247, 2993-3012.
H. El Cadi, H. El Bouzidi, G. Selama, B. Ramdan, Y. Oulad El Majdoub, F. Alibrando, K. Arena, M. Palma Lovillo, J. Brigui, L. Mondello, F. Cacciola, T. M. G. Salerno, Molecules 2021, 26, 2710.
M. Ohnishi, H. Morishita, H. Iwahashi, T. Shitzuo, S. Yoshiaki, M. Kimura, R. Kido, Phytochemistry 1994, 36, 579-583.
M. Oyaizu, Jpn. J. Nutr. Diet. 1986, 44, 307-315.
T. S. Kumar, S. Shanmugam, T. Palvannan, V. M. B. Kumar, Iran. J. Pharm. Res. 2008, 7, 211-215.
Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. CLSI, Wayne, PA, USA: 2018.
Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved Standard M27-A3, CLSI, Wayne, PA, USA, 2008.
B. N. Meyer, N. R. Ferrigni, J. E. Putnam, L. B. Jacobson, D. E. Nichols, J. L. McLaughlin, Planta Med. 1982, 45, 31-34.

Auteurs

Paola Arena (P)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.
Foundation "Prof. Antonio Imbesi", University of Messina, Piazza Pugliatti 1, 98122, Messina, Italy.

Natalizia Miceli (N)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.

Andreana Marino (A)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.

Federica Davì (F)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.
Foundation "Prof. Antonio Imbesi", University of Messina, Piazza Pugliatti 1, 98122, Messina, Italy.

Emilia Cavò (E)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.
Foundation "Prof. Antonio Imbesi", University of Messina, Piazza Pugliatti 1, 98122, Messina, Italy.

Vivienne Spadaro (V)

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, Section of Botany, Anthropology and Zoology, University of Palermo, Via Archirafi 38, 90123, Palermo, Italy.

Francesco Maria Raimondo (FM)

PLANTA/Research, Documentation and Training Center, Via Serraglio Vecchio 28, 90123, Palermo, Italy.

Francesco Cacciola (F)

Department of Biomedical, Dental, Morphological and Functional Imaging Sciences, University of Messina, Via Consolare Valeria, 98125, Messina, Italy.

Roberto Laganà Vinci (R)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.

Luigi Mondello (L)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.
Chromaleont s.r.l., c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Palatucci, 98168, Messina, Italy.
Department of Sciences and Technologies for Human and Environment, University Campus Bio-Medico of Rome, via Àlvaro del Portillo 21, 00128, Rome, Italy.

Maria Fernanda Taviano (MF)

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166, Messina, Italy.

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