Modeling human health behavior with a new index that measures connectivity.

Abstinence Adherence Graph theory Health behavior Network analysis

Journal

Preventive medicine reports
ISSN: 2211-3355
Titre abrégé: Prev Med Rep
Pays: United States
ID NLM: 101643766

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 18 07 2022
revised: 31 01 2023
accepted: 05 03 2023
medline: 24 5 2023
pubmed: 24 5 2023
entrez: 24 5 2023
Statut: epublish

Résumé

Health behavior is an important determinant of health. Adherence to medication and abstinence from harmful substances are two critical health behaviors. Although conceptually related, both are assessed using disparate measures. The goal of this study was to develop and test a new index, gamma, which models health behavior by quantifying the connectedness of discrete incidents of health behavior. We derive gamma from first principles and use it to reanalyze data from a published trial of treatment for alcohol use disorders. We model a primary endpoint, changes in binge drinking, using gamma and a traditional measure: change in number of monthly binges. The original trial was conducted in an urban hospital emergency department in the U.S. Incorporating gamma into the model provided additional insights into the relationship between the intervention and long-term changes in drinking. Gamma provides an additional tool to model the effects of interventions on outcomes in trials of substance use interventions or medication adherence. Gamma measures the pattern of behavior and may increase the explanatory power of models assessing differences between various treatments. The gamma index offers the possibility of novel real-time interventions to promote healthy behaviors.

Identifiants

pubmed: 37223571
doi: 10.1016/j.pmedr.2023.102172
pii: S2211-3355(23)00063-3
pmc: PMC10201843
doi:

Types de publication

Journal Article

Langues

eng

Pagination

102172

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Steven L Bernstein (SL)

Department of Emergency Medicine, Yale School of Medicine, United States.
Yale Cancer Center, Yale School of Medicine, United States.

Fangyong Li (F)

Yale Center of Analytical Science, Yale School of Medicine, United States.

Fuad Abujarad (F)

Department of Emergency Medicine, Yale School of Medicine, United States.

David R Grant (DR)

Department of Mathematics, University of Colorado, Boulder, CO, United States.

Gail D'Onofrio (G)

Department of Emergency Medicine, Yale School of Medicine, United States.
Yale School of Public Health, Yale School of Medicine, United States.

James Dziura (J)

Department of Emergency Medicine, Yale School of Medicine, United States.
Yale Center of Analytical Science, Yale School of Medicine, United States.

Classifications MeSH