Cellular drug delivery system for disease treatment.

Drug Delivery Systems
Cell carrier Cell engineering Cell therapy Cellular drug delivery Nanoparticles

Journal

International journal of pharmaceutics
ISSN: 1873-3476
Titre abrégé: Int J Pharm
Pays: Netherlands
ID NLM: 7804127

Informations de publication

Date de publication:
25 Jun 2023
Historique:
received: 05 02 2023
revised: 08 05 2023
accepted: 21 05 2023
medline: 14 6 2023
pubmed: 25 5 2023
entrez: 24 5 2023
Statut: ppublish

Résumé

The application of variable novel drug delivery system has shown a flowering trend in recent years. Among them, the cell-based drug delivery system (DDS) utilizes the unique physiological function of cells to deliver drugs to the lesion area, which is the most complex and intelligent DDS at present. Compared with the traditional DDS, the cell-based DDS has the potential of prolonged circulation in body. Cellular DDS is expected to be the best carrier to realize multifunctional drug delivery. This paper introduces and analyzes common cellular DDSs such as blood cells, immune cells, stem cells, tumor cells and bacteria as well as relevant research examples in recent years. We hope that this review can provide a reference for future research on cell vectors and promote the innovative development and clinical transformation of cell-based DDS.

Identifiants

DOI: 10.1016/j.ijpharm.2023.123069 PMID: 37225024
pubmed: 37225024
pii: S0378-5173(23)00489-1
doi: 10.1016/j.ijpharm.2023.123069
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

123069

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Luyue Wang (L)

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China.

Yu Zhang (Y)

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China.

Yukun Ma (Y)

Department of Pharmacy, Jinan Stomatologic Hospital, Jinan, Shandong 250001, PR China.

Yujia Zhai (Y)

Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah 84124, USA.

Jianbo Ji (J)

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China. Electronic address: jijianbo@sdu.edu.cn.

Xiaoye Yang (X)

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China. Electronic address: yangxiaoye@sdu.edu.cn.

Guangxi Zhai (G)

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China. Electronic address: professorgxzhai@126.com.

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Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Cellular drug delivery system for disease treatment.