UHRF1 is essential for proper cytoplasmic architecture and function of mouse oocytes and derived embryos.
Journal
Life science alliance
ISSN: 2575-1077
Titre abrégé: Life Sci Alliance
Pays: United States
ID NLM: 101728869
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
06
01
2023
revised:
14
05
2023
accepted:
15
05
2023
medline:
26
5
2023
pubmed:
25
5
2023
entrez:
24
5
2023
Statut:
epublish
Résumé
Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is a protein essential for the maintenance of DNA methylation in somatic cells. However, UHRF1 is predominantly localized in the cytoplasm of mouse oocytes and preimplantation embryos, where it may play a role unrelated to the nuclear function. We herein report that oocyte-specific
Identifiants
pubmed: 37225425
pii: 6/8/e202301904
doi: 10.26508/lsa.202301904
pmc: PMC10209520
pii:
doi:
Substances chimiques
Uhrf1 protein, mouse
EC 2.3.2.27
CCAAT-Enhancer-Binding Proteins
0
Ubiquitin-Protein Ligases
EC 2.3.2.27
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2023 Uemura et al.
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