Binocular metamorphopsia in patients with branch retinal vein occlusion: a multi-center study.


Journal

International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 21 07 2022
accepted: 22 04 2023
medline: 4 8 2023
pubmed: 25 5 2023
entrez: 25 5 2023
Statut: ppublish

Résumé

The pathology of branch retinal vein occlusion (BRVO), a retinal circulatory disease, is related to monocular metamorphopsia-related vision impairment of the affected eyes, but the association of binocular metamorphopsia in such patients is unclear. This study aimed to examine the frequency of binocular metamorphopsia and its association with the clinical characteristics of patients with BRVO. A total of 87 patients who were treated for BRVO-associated macular edema (ME) were included in this study. At baseline and 1 and 3 months after the initiation of anti-vascular endothelial growth factor (VEGF) treatment, we quantified metamorphopsia in the affected eyes and binocular metamorphopsia using the M-CHARTS At baseline, 53 and 7 patients had metamorphopsia in the affected eyes and binocular metamorphopsia, respectively. Although the visual acuity improved significantly after the initiation of anti-VEGF treatment, the mean M-CHARTS score in the affected eyes did not change from the baseline score. At 3 months, 9 patients showed binocular metamorphopsia; it was significantly associated with metamorphopsia in the affected eyes with a 95% confidence interval of 0.021-0.122 (β = 0.306, p = 0.006). Metamorphopsia in the affected eyes can cause binocular metamorphopsia in patients with BRVO-ME.

Identifiants

pubmed: 37227617
doi: 10.1007/s10792-023-02731-0
pii: 10.1007/s10792-023-02731-0
pmc: PMC10400688
doi:

Substances chimiques

Vascular Endothelial Growth Factor A 0
Angiogenesis Inhibitors 0

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3279-3286

Informations de copyright

© 2023. The Author(s).

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Auteurs

Rie Osaka (R)

Department of Ophthalmology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Yuki Muraoka (Y)

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. muraoka@kuhp.kyoto-u.ac.jp.

Daisuke Nagasato (D)

Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School, Hiroshima, Japan.
Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Yoshinori Mitamura (Y)

Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School, Hiroshima, Japan.

Naomi Nishigori (N)

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Tomoaki Murakami (T)

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Kiyoshi Suzuma (K)

Department of Ophthalmology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Hitoshi Tabuchi (H)

Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
Department of Technology and Design Thinking for Medicine, Hiroshima University Graduate School, Hiroshima, Japan.
Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Akitaka Tsujikawa (A)

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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Classifications MeSH