Public health evaluation of PFAS exposures and breastfeeding: a systematic literature review.
PFAS
PFOA
PFOS
breastfeeding
lactation
nursing
Journal
Toxicological sciences : an official journal of the Society of Toxicology
ISSN: 1096-0929
Titre abrégé: Toxicol Sci
Pays: United States
ID NLM: 9805461
Informations de publication
Date de publication:
28 07 2023
28 07 2023
Historique:
pmc-release:
28
07
2024
medline:
31
7
2023
pubmed:
25
5
2023
entrez:
25
5
2023
Statut:
ppublish
Résumé
Per- and polyfluoroalkyl substances (PFAS) are a class of man-made chemicals that are persistent in the environment. They can be transferred across the placenta to fetuses and through human milk to infants. The American Academy of Pediatrics advises that the benefits of breastfeeding infants almost always outweigh the potential risks of harm from environmental chemicals. However, there are few chemical-specific summaries of the potential harms of exposure to PFAS during the neonatal period through breastfeeding. This systematic review explores whether exposure to PFAS through breastfeeding is associated with adverse health outcomes among infants and children using evidence from human and animal studies. Systematic searches identified 4297 unique records from 7 databases. The review included 37 total articles, including 9 animal studies and 1 human study measuring the direct contribution of exposure of the infant or pup through milk for any health outcome. Animal studies provided evidence of associations between exposure to PFOA through breastfeeding and reduced early life body weight gain, mammary gland development, and thyroid hormone levels. They also provided limited evidence of associations between PFOS exposure through breastfeeding with reduced early life body weight gain and cellular changes in the hippocampus. The direct relevance of any of these outcomes to human health is uncertain, and it is possible that many adverse health effects of exposure through breastfeeding have not yet been studied. This review documents the current state of science and highlights the need for future research to guide clinicians making recommendations on infant feeding.
Identifiants
pubmed: 37228093
pii: 7179809
doi: 10.1093/toxsci/kfad053
pmc: PMC10527886
mid: NIHMS1916286
doi:
Substances chimiques
Fluorocarbons
0
Alkanesulfonic Acids
0
Environmental Pollutants
0
Types de publication
Systematic Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
121-137Subventions
Organisme : Intramural CDC HHS
ID : CC999999
Pays : United States
Informations de copyright
Published by Oxford University Press on behalf of the Society of Toxicology 2023.
Références
Obstet Gynecol. 2009 May;113(5):974-982
pubmed: 19384111
Pediatrics. 2013 Sep;132(3):e796-809
pubmed: 23979084
Toxicology. 2005 Nov 5;215(1-2):126-48
pubmed: 16146667
JAMA. 2005 Nov 23;294(20):2601-10
pubmed: 16304074
J Immunotoxicol. 2017 Dec;14(1):188-195
pubmed: 28805477
Neurotoxicol Teratol. 2021 Nov-Dec;88:107022
pubmed: 34438039
Reprod Toxicol. 2009 Jun;27(3-4):319-330
pubmed: 19162172
Reprod Toxicol. 2009 Jun;27(3-4):239-245
pubmed: 19429402
Toxicol Sci. 2010 May;115(1):214-24
pubmed: 20118188
Toxicol Pathol. 2012 Oct;40(7):971-94
pubmed: 22723046
Curr Environ Health Rep. 2018 Mar;5(1):1-19
pubmed: 29556975
Matern Child Nutr. 2009 Jul;5(3):199-210
pubmed: 19531047
Environ Int. 2017 Dec;109:128-135
pubmed: 28890218
Environ Health. 2014 Dec 10;13:106
pubmed: 25495114
Environ Sci Technol. 2017 May 16;51(10):5756-5763
pubmed: 28434222
Environ Health Perspect. 2018 Oct;126(10):104501
pubmed: 30392397
Cancer Causes Control. 2012 Jun;23(6):919-27
pubmed: 22527170
Am J Physiol Lung Cell Mol Physiol. 2014 Nov 15;307(10):L765-74
pubmed: 25217661
Environ Epidemiol. 2018 Jun;2(2):
pubmed: 30272047
Toxicol Sci. 2007 Feb;95(2):452-61
pubmed: 17093205
Int J Environ Res Public Health. 2017 Jun 27;14(7):
pubmed: 28654008
Environ Sci Technol. 2008 Nov 15;42(22):8597-602
pubmed: 19068854
Environ Int. 2019 Mar;124:482-492
pubmed: 30684806
Neurotoxicology. 2010 Sep;31(5):424-31
pubmed: 20609431
Toxicol Sci. 2009 Sep;111(1):89-99
pubmed: 19407336
Clin Perinatol. 2017 Mar;44(1):49-67
pubmed: 28159209
Environ Health Perspect. 2018 Sep;126(9):96002
pubmed: 30256157
Environ Int. 2016 Dec;97:237-245
pubmed: 27692925
Pediatrics. 2022 Jul 1;150(1):
pubmed: 35921641
JAMA. 2012 Jan 25;307(4):391-7
pubmed: 22274686
Environ Toxicol Chem. 2021 Mar;40(3):606-630
pubmed: 33017053
Sci Total Environ. 2021 Feb 10;755(Pt 2):142697
pubmed: 33065506
Sci Total Environ. 2021 Jun 20;774:144795
pubmed: 33609849
Pediatrics. 2011 Jul;128(1):103-10
pubmed: 21669892
Environ Health Perspect. 2014 Oct;122(10):1040-51
pubmed: 24968389
Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105
pubmed: 19433254
Reprod Toxicol. 2009 Jun;27(3-4):289-298
pubmed: 19095057
Arch Toxicol. 2020 Jun;94(6):2131-2147
pubmed: 32227269
Environ Sci Technol. 2008 Apr 15;42(8):3096-101
pubmed: 18497172
Environ Health Perspect. 2020 May;128(5):57002
pubmed: 32378965
Environ Health Perspect. 2011 Aug;119(8):1070-6
pubmed: 21501981
Environ Health Perspect. 2022 Feb;130(2):25002
pubmed: 35195447
Hum Reprod. 2013 Dec;28(12):3337-48
pubmed: 24129614
Integr Environ Assess Manag. 2011 Oct;7(4):513-41
pubmed: 21793199
Nat Rev Endocrinol. 2017 Mar;13(3):161-173
pubmed: 27857130
Toxicol Sci. 2007 Feb;95(2):462-73
pubmed: 17098816
Arch Intern Med. 2009 Aug 10;169(15):1364-71
pubmed: 19667298
Environ Toxicol. 2015 Sep;30(9):1082-90
pubmed: 24616003
Lancet. 1990 Dec 22-29;336(8730):1519-23
pubmed: 1979363
Environ Int. 2015 Oct;83:176-82
pubmed: 26159671
Arch Toxicol. 2016 Mar;90(3):701-15
pubmed: 25827101
Environ Health Perspect. 2012 Oct;120(10):1432-7
pubmed: 22935244
Food Chem Toxicol. 2015 Feb;76:70-6
pubmed: 25524167
Drug Chem Toxicol. 2008;31(3):317-37
pubmed: 18622868
Environ Sci Technol. 2021 Jun 1;55(11):7510-7520
pubmed: 33982557
Arch Toxicol. 2010 Jan;84(1):71-9
pubmed: 19756518
Environ Sci Technol. 2009 Nov 1;43(21):8416-22
pubmed: 19924978
Environ Int. 2011 Jan;37(1):129-35
pubmed: 20843552
Neurotox Res. 2011 Apr;19(3):452-61
pubmed: 20512442
Environ Health Perspect. 2014 Oct;122(10):1015-27
pubmed: 24968374
Am J Epidemiol. 2010 Dec 1;172(11):1230-7
pubmed: 20940176
Environ Sci Technol. 2015 Sep 1;49(17):10466-73
pubmed: 26291735
Environ Int. 2022 Jun;164:107274
pubmed: 35524998
Environ Health Perspect. 2014 Feb;122(2):187-92
pubmed: 24280536
Environ Health Perspect. 2018 Sep;126(9):96001
pubmed: 30187772
Ecotoxicol Environ Saf. 2022 Aug;241:113818
pubmed: 35777342
Reprod Toxicol. 2015 Jul;54:26-36
pubmed: 25499722
Environ Health Perspect. 2014 Oct;122(10):1028-39
pubmed: 24968388
Environ Health Perspect. 2015 Dec;123(12):1317-24
pubmed: 26008903
Toxicol Sci. 2007 Mar;96(1):133-44
pubmed: 17132714
Annu Rev Pharmacol Toxicol. 2012;52:455-79
pubmed: 22017681
Environ Int. 2010 Aug;36(6):584-92
pubmed: 20494442
Environ Sci Technol. 2010 Mar 1;44(5):1847-53
pubmed: 20136073
J Mammary Gland Biol Neoplasia. 1999 Jan;4(1):53-68
pubmed: 10219906
J Expo Sci Environ Epidemiol. 2019 Mar;29(2):131-147
pubmed: 30470793
Environ Sci Eur. 2018;30(1):9
pubmed: 29527446
Environ Int. 2018 Dec;121(Pt 1):591-599
pubmed: 30308470
Sci Total Environ. 2013 Mar 1;447:430-7
pubmed: 23410865