Encephalitis and Meningitis: Indications for Intervention.
CNS inflammation
Diagnostic criteria
Emerging therapies
Encephalitis
Encephalitis treatment
ICP
Immunomodulatory therapies
Meningitis
Meningitis treatment
Meningoencephalitis
Journal
Clinical research (Westerville, Ohio)
Titre abrégé: Clin Res (Westerville)
Pays: United States
ID NLM: 9918609980006676
Informations de publication
Date de publication:
2023
2023
Historique:
medline:
25
5
2023
pubmed:
25
5
2023
entrez:
25
5
2023
Statut:
ppublish
Résumé
Meningitis and encephalitis are characterized by inflammation of the meninges and brain parenchyma, respectively. The blood-brain barrier normally acts as a protective barrier against inflammation in the central nervous system (CNS), but its compromise requires prompt diagnosis and treatment to prevent morbidity and mortality. Optimizing therapy for meningitis and encephalitis can expedite resolution of symptoms, mitigating the risk of neuronal injury and minimizing potential long-term neurological sequelae. This paper aims to provide a comprehensive overview of the etiology and pathophysiology of meningitis and encephalitis, discussing the diagnostic criteria, and emphasizing the clinical indications for treatments, including current treatment strategies, and emerging therapeutic approaches.
Identifiants
pubmed: 37229501
pmc: PMC10207635
mid: NIHMS1896214
pii:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NINDS NIH HHS
ID : R25 NS108939
Pays : United States
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